Luke W. Paine

Tennis Court Road
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 10 publications

Cromolyn inhibits PGE2-mediated sensitisation of TRPV1 in a GPR35-dependent manner in sensory neurons.

Cromolyn inhibits PGE2-mediated sensitisation of TRPV1 in a GPR35-dependent manner in sensory neurons.

Journal: Neuroscience letters

Published: February 20, 2026

Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease.

Monoclonal antibody inhibition of PAR2 reduces phenotype severity and pain in murine inflammatory bowel disease.

Journal: Pain reports

Published: January 09, 2026

Age-Related Loss of GPR68 and Calretinin Immunoreactive Neurons Within the Mucosa, Not the Myenteric Plexus of Human Colon.

Age-Related Loss of GPR68 and Calretinin Immunoreactive Neurons Within the Mucosa, Not the Myenteric Plexus of Human Colon.

Journal: British journal of biomedical science

Published: November 11, 2025

Cap-independent co-expression of dsRNA-sensing and NF-κB pathway inhibitors enables controllable self-amplifying RNA expression with reduced immunotoxicity.

Cap-independent co-expression of dsRNA-sensing and NF-κB pathway inhibitors enables controllable self-amplifying RNA expression with reduced immunotoxicity.

Journal: eLife

Published: August 29, 2025

GPR68, A Proton-sensing GPCR, Mediates Acid-induced Visceral Nociception.

GPR68, A Proton-sensing GPCR, Mediates Acid-induced Visceral Nociception.

Journal: Cellular and molecular gastroenterology and hepatology

Published: June 13, 2025

IL-17 Stimulates Sensory Neurons and Sensitises Colonic Afferents to Noxious Stimuli in a PI3K Dependent Manner in Male Mice.

IL-17 Stimulates Sensory Neurons and Sensitises Colonic Afferents to Noxious Stimuli in a PI3K Dependent Manner in Male Mice.

Journal: Journal of neurochemistry

Published: April 16, 2025

Pro-inflammatory mediators sensitise transient receptor potential melastatin 3 cation channel (TRPM3) function in mouse sensory neurons.

Pro-inflammatory mediators sensitise transient receptor potential melastatin 3 cation channel (TRPM3) function in mouse sensory neurons.

Journal: Neuropharmacology

Published: September 10, 2024

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate.

TRPV4 stimulates colonic afferents through mucosal release of ATP and glutamate.

Journal: British journal of pharmacology

Published: June 03, 2024

GPR35 agonists inhibit TRPA1-mediated colonic nociception through suppression of substance P release.

GPR35 agonists inhibit TRPA1-mediated colonic nociception through suppression of substance P release.

Journal: Pain

Published: February 12, 2024

Digging deeper into pain: an ethological behavior assay correlating well-being in mice with human pain experience.

Digging deeper into pain: an ethological behavior assay correlating well-being in mice with human pain experience.

Journal: Pain

Published: August 22, 2023

Showing 1-10 of 10

Last Updated: 09/26/2026