Lulzim Shkreta

Quebec, QC, Canada

Last Updated: 09/26/2026

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Found 19 publications

RNA-based discovery and correction of splicing defects caused by POLR3A missense mutations.

RNA-based discovery and correction of splicing defects caused by POLR3A missense mutations.

Journal: Molecular therapy. Nucleic acids
Published: November 07, 2025

Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals.

Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals.

Journal: Viruses
Published: November 26, 2024

Regulatory interplay between SR proteins governs CLK1 kinase splice variants production.

Regulatory interplay between SR proteins governs CLK1 kinase splice variants production.

Journal: RNA (New York, N.Y.)
Published: May 20, 2024

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response.

The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response.

Journal: Oncotarget
Published: May 16, 2024

Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency.

Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency.

Journal: Retrovirology
Published: March 17, 2022

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation.

Journal: Viruses
Published: November 26, 2021

SRSF10: an atypical splicing regulator with critical roles in stress response, organ development, and viral replication.

SRSF10: an atypical splicing regulator with critical roles in stress response, organ development, and viral replication.

Journal: RNA (New York, N.Y.)
Published: July 28, 2021

Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond.

Interplay Between CMGC Kinases Targeting SR Proteins and Viral Replication: Splicing and Beyond.

Journal: Frontiers in microbiology
Published: January 27, 2021

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.

Journal: NAR cancer
Published: November 11, 2020

Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

Journal: Brain : a journal of neurology
Published: October 27, 2018

hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.

hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage.

Journal: Scientific reports
Published: May 16, 2017

TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.

TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.

Journal: Brain : a journal of neurology
Published: May 11, 2017
Showing 1-12 of 19

Last Updated: 09/26/2026