Lynsey R. Chatham

2, James Lindsay Place, Dundee Technopole
Dundee, SCT DD15JJ, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

Correction: The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.

Correction: The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.

Journal: Archives of toxicology
Published: June 26, 2026

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals.

Journal: Archives of toxicology
Published: January 16, 2025

Mode of action analysis for fluxapyroxad-induced rat liver tumour formation: evidence for activation of the constitutive androstane receptor and assessment of human relevance.

Mode of action analysis for fluxapyroxad-induced rat liver tumour formation: evidence for activation of the constitutive androstane receptor and assessment of human relevance.

Journal: Toxicology
Published: January 18, 2024

Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats.

Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats.

Journal: Toxicology
Published: May 11, 2020

Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance.

Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance.

Journal: Toxicology
Published: January 27, 2020

Comparative studies on the effects of sodium phenobarbital and two other constitutive androstane receptor (CAR) activators on induction of cytochrome P450 enzymes and replicative DNA synthesis in cultured hepatocytes from wild type and CAR knockout rats.

Comparative studies on the effects of sodium phenobarbital and two other constitutive androstane receptor (CAR) activators on induction of cytochrome P450 enzymes and replicative DNA synthesis in cultured hepatocytes from wild type and CAR knockout rats.

Journal: Toxicology
Published: November 12, 2019

An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.

An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.

Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: June 11, 2019

Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance.

Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance.

Journal: Toxicology
Published: April 07, 2019

Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats.

Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: February 10, 2018

Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.

Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.

Journal: Toxicology
Published: November 29, 2017

Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.

Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.

Journal: Toxicology
Published: November 28, 2017

A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity.

A functional SUMO-motif in the active site of PIM1 promotes its degradation via RNF4, and stimulates protein kinase activity.

Journal: Scientific reports
Published: December 20, 2016
Showing 1-12 of 14

Last Updated: 09/26/2026