Madeleine Speck - Publications

CAR Treg synergy with anti-CD154 promotes infectious tolerance and dictates allogeneic heart transplant acceptance.

Journal: JCI insight

Published: November 01, 2024

CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes.

Journal: bioRxiv : the preprint server for biology

Published: October 10, 2024

Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection.

Journal: JCI insight

Published: November 16, 2022

PTEN is required for human Treg suppression of costimulation in vitro.

Journal: European journal of immunology

Published: March 07, 2022

Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells.

Journal: Science translational medicine

Published: September 12, 2019

Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Published: June 08, 2019

Islet Macrophages Shift to a Reparative State following Pancreatic Beta-Cell Death and Are a Major Source of Islet Insulin-like Growth Factor-1.

Journal: iScience

Published: January 04, 2019

Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells.

Journal: JCI insight

Published: July 18, 2018

Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.

Journal: Diabetes

Published: May 09, 2014

Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: December 11, 2013

TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6.

Journal: Diabetologia

Published: October 28, 2013