Magnus Doverskog
Karolinska Institute Science Park
Solna, AB, Sweden
Solna, AB, Sweden
Last Updated: 09/26/2026
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Found 16 publications
Golexanolone Attenuates Neuroinflammation, Fatigue, and Cognitive and Motor Impairment in Diverse Neuroinflammatory Disorders.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: October 14, 2025
Golexanolone affords sustained improvement of Parkinson's symptoms in rats by reducing microglia activation that restores the glutamate-GABA-dopamine pathway.
Journal: Neuropharmacology
Published: July 10, 2025
Golexanolone reduces glial activation in the striatum and improves non-motor and some motor alterations in a rat model of Parkinson's disease.
Journal: Frontiers in aging neuroscience
Published: April 15, 2024
Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications.
Journal: Frontiers in pharmacology
Published: December 19, 2023
Allopregnanolone and its antagonist modulate neuroinflammation and neurological impairment.
Journal: Neuroscience and biobehavioral reviews
Published: October 19, 2023
Extra-Synaptic GABAA Receptor Potentiation and Neurosteroid-Induced Learning Deficits Are Inhibited by GR3027, a GABAA Modulating Steroid Antagonist.
Journal: Biomolecules
Published: August 19, 2023
The GABA system, a new target for medications against cognitive impairment-Associated with neuroactive steroids.
Journal: Journal of internal medicine
Published: July 30, 2023
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
Journal: Liver international : official journal of the International Association for the Study of the Liver
Published: May 26, 2023
Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?
Journal: Canadian journal of gastroenterology & hepatology
Published: June 13, 2022
Golexanolone, a GABAA receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation.
Journal: CNS neuroscience & therapeutics
Published: May 12, 2022
A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy.
Journal: Journal of hepatology
Published: November 12, 2020
Last Updated: 09/26/2026