Mahendiran Dharmasivam

Griffith University Parklands Drive Gold Coast Queensland 4222 Australia
Gold Coast, QLD 4222, Australia

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 33 publications

Fine-tuning thiosemicarbazones with heterocyclic substituents: identification of styryl-dependent cysteine reactivity and potent anti-cancer activity.

Fine-tuning thiosemicarbazones with heterocyclic substituents: identification of styryl-dependent cysteine reactivity and potent anti-cancer activity.

Journal: Chemical science

Published: March 17, 2026

Artificial intelligence-assisted drug discovery in 2025: Faster, but is it better? The robots are coming, look out!

Artificial intelligence-assisted drug discovery in 2025: Faster, but is it better? The robots are coming, look out!

Journal: Pharmacological reviews

Published: December 03, 2025

Transmetalation in Cancer Pharmacology.

Transmetalation in Cancer Pharmacology.

Journal: International journal of molecular sciences

Published: October 20, 2025

Lysosome as a Chemical Reactor.

Lysosome as a Chemical Reactor.

Journal: International journal of molecular sciences

Published: October 14, 2025

Leading artificial intelligence-driven drug discovery platforms: 2025 landscape and global outlook.

Leading artificial intelligence-driven drug discovery platforms: 2025 landscape and global outlook.

Journal: Pharmacological reviews

Published: September 10, 2025

Implementing the design cues of dissociation dynamics and transmetalation in gallium(iii) complexes to promote the anti-proliferative activity of ligands targeting intracellular iron(ii) trafficking.

Implementing the design cues of dissociation dynamics and transmetalation in gallium(iii) complexes to promote the anti-proliferative activity of ligands targeting intracellular iron(ii) trafficking.

Journal: Chemical science

Published: August 11, 2025

Metal-based antibody, nanobody, and peptide conjugates: Potential for breast cancer therapy.

Metal-based antibody, nanobody, and peptide conjugates: Potential for breast cancer therapy.

Journal: Pharmacological reviews

Published: June 26, 2025

Advantages of Novel Anti-cancer Selenosemicarbazones: Preferential Reactivity of Their Fe(III), Cu(II), and Zn(II) Complexes with Key Physiological Reductants/Ligands Versus Isosteric Thiosemicarbazones.

Advantages of Novel Anti-cancer Selenosemicarbazones: Preferential Reactivity of Their Fe(III), Cu(II), and Zn(II) Complexes with Key Physiological Reductants/Ligands Versus Isosteric Thiosemicarbazones.

Journal: Journal of medicinal chemistry

Published: April 23, 2025

NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones.

NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones.

Journal: The Journal of biological chemistry

Published: March 15, 2025

Innovative N-Acridine Thiosemicarbazones and Their Zn(II) Complexes Transmetallate with Cu(II): Redox Activity and Suppression of Detrimental Oxy-Myoglobin Oxidation.

Innovative N-Acridine Thiosemicarbazones and Their Zn(II) Complexes Transmetallate with Cu(II): Redox Activity and Suppression of Detrimental Oxy-Myoglobin Oxidation.

Journal: Inorganic chemistry

Published: October 15, 2024

Biomolecular Interactions and Anticancer Mechanisms of Ru(II)-Arene Complexes of Cinnamaldehyde-Derived Thiosemicarbazone Ligands: Analysis Combining In Silico and In Vitro Approaches.

Biomolecular Interactions and Anticancer Mechanisms of Ru(II)-Arene Complexes of Cinnamaldehyde-Derived Thiosemicarbazone Ligands: Analysis Combining In Silico and In Vitro Approaches.

Journal: ACS applied bio materials

Published: August 01, 2024

Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy.

Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn(II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy.

Journal: Journal of medicinal chemistry

Published: July 05, 2024

Showing 1-12 of 33

Last Updated: 09/26/2026