Mahendra Madegowda
Mysore, KA 570006, India
Last Updated: 09/26/2026
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Found 25 publications
Targeting c-Met and EMT, PI3K/Akt/mTOR/MEK signaling with Dihydropyrimidinone-Piperazine-based scaffold that triggers apoptosis, autophagy, and paraptosis in breast carcinomas.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: November 07, 2025
Exploring the binding dynamics of triazolyl-thio-oxazines for MDM2-p53 disruption: Design, synthesis, and p53 upregulation.
Journal: International journal of biological macromolecules
Published: August 16, 2025
Targeting breast cancer cells with 2-indolyl-1,3,4-oxadiazole compounds by inducing apoptosis, paraptosis and autophagy.
Journal: Chemico-biological interactions
Published: December 06, 2024
Probing the hybridized triazole-chalcones: an in-depth investigations of molecular structure journey towards antibacterial potential against DNA gyrase.
Journal: Journal of biomolecular structure & dynamics
Published: November 22, 2024
Isoxazole based nucleosides induce autophagy through the production of ROS and the suppression of the β-catenin pathway in human colorectal carcinoma cells.
Journal: Chemico-biological interactions
Published: July 17, 2024
Pyrimidine-triazole-tethered tert-butyl-piperazine-carboxylate suppresses breast cancer by targeting estrogen receptor signaling and β-catenin activation.
Journal: IUBMB life
Published: May 23, 2024
Thiouracil and triazole conjugate induces autophagy through the downregulation of Wnt/β-catenin signaling pathway in human breast cancer cells.
Journal: IUBMB life
Published: May 21, 2024
A novel drug prejudice scaffold-imidazopyridine-conjugate can promote cell death in a colorectal cancer model by binding to β-catenin and suppressing the Wnt signaling pathway.
Journal: Journal of advanced research
Published: March 28, 2024
Oxazine drug-seed induces paraptosis and apoptosis through reactive oxygen species/JNK pathway in human breast cancer cells.
Journal: Translational oncology
Published: March 15, 2024
Discovery of oxazine-linked pyrimidine as an inhibitor of breast cancer growth and metastasis by abrogating NF-κB activation.
Journal: Frontiers in oncology
Published: February 24, 2024
Chalcone-based Turn-Off Chemosensor for Selective and Susceptible Detection of Fe2+ Ions: Spectroscopic and DFT Investigations.
Journal: Journal of fluorescence
Published: January 21, 2024
Last Updated: 09/26/2026