Mahnaz Mellati

Mahnaz Mellati

Endocrinology
904 7th Avenue
Seattle, WA 98104

Last Updated: 09/26/2026

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Found 7 publications

Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.

Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.

Journal: Diabetologia
Published: April 01, 2020

Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice.

Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice.

Journal: Protein engineering, design & selection : PEDS
Published: June 03, 2019

Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation.

Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation.

Journal: Diabetes
Published: November 03, 2016

Inhibition of Insulin-Degrading Enzyme Does Not Increase Islet Amyloid Deposition in Vitro.

Inhibition of Insulin-Degrading Enzyme Does Not Increase Islet Amyloid Deposition in Vitro.

Journal: Endocrinology
Published: July 13, 2016

The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.

The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.

Journal: Diabetologia
Published: August 21, 2015

Anti-PD-1 and Anti-PDL-1 Monoclonal Antibodies Causing Type 1 Diabetes.

Anti-PD-1 and Anti-PDL-1 Monoclonal Antibodies Causing Type 1 Diabetes.

Journal: Diabetes care
Published: April 25, 2015

Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.

Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.

Journal: Cell metabolism
Published: October 12, 2012
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Last Updated: 09/26/2026