Mai S. Shoukrofy-El

Alexandria, ALX 21521, Egypt

Last Updated: 09/26/2026

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Found 12 publications

Novel benzoxazole-based hybrids as multi-target inhibitors of aromatase, EGFR, and PI3K with potential anti-breast cancer activity.

Novel benzoxazole-based hybrids as multi-target inhibitors of aromatase, EGFR, and PI3K with potential anti-breast cancer activity.

Journal: Bioorganic & medicinal chemistry

Published: September 19, 2025

Novel furanone-based anticancer agents: Design, synthesis, Hsp90 inhibition, in vivo antitumor activity and pharmacokinetic studies.

Novel furanone-based anticancer agents: Design, synthesis, Hsp90 inhibition, in vivo antitumor activity and pharmacokinetic studies.

Journal: European journal of medicinal chemistry

Published: July 30, 2025

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation.

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation.

Journal: European journal of medicinal chemistry

Published: December 22, 2024

Challenging the Biginelli scaffold to surpass the first line antitubercular drugs: Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibition activity and molecular modelling studies.

Challenging the Biginelli scaffold to surpass the first line antitubercular drugs: Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) inhibition activity and molecular modelling studies.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: September 11, 2024

New tetrahydropyrimidine-1,2,3-triazole clubbed compounds: Antitubercular activity and Thymidine Monophosphate Kinase (TMPKmt) inhibition.

New tetrahydropyrimidine-1,2,3-triazole clubbed compounds: Antitubercular activity and Thymidine Monophosphate Kinase (TMPKmt) inhibition.

Journal: Bioorganic chemistry

Published: September 16, 2022

Antiproliferative activity, enzymatic inhibition and apoptosis-promoting effects of benzoxazole-based hybrids on human breast cancer cells.

Antiproliferative activity, enzymatic inhibition and apoptosis-promoting effects of benzoxazole-based hybrids on human breast cancer cells.

Journal: Bioorganic chemistry

Published: August 21, 2020

Benzoxazole derivatives as new generation of anti-breast cancer agents.

Benzoxazole derivatives as new generation of anti-breast cancer agents.

Journal: Bioorganic chemistry

Published: September 18, 2019

Design and synthesis of some β-carboline derivatives as multi-target anticancer agents.

Design and synthesis of some β-carboline derivatives as multi-target anticancer agents.

Journal: Future medicinal chemistry

Published: December 13, 2018

Pyrazoles containing thiophene, thienopyrimidine and thienotriazolopyrimidine as COX-2 selective inhibitors: Design, synthesis, in vivo anti-inflammatory activity, docking and in silico chemo-informatic studies.

Pyrazoles containing thiophene, thienopyrimidine and thienotriazolopyrimidine as COX-2 selective inhibitors: Design, synthesis, in vivo anti-inflammatory activity, docking and in silico chemo-informatic studies.

Journal: Bioorganic chemistry

Published: November 20, 2018

Design, synthesis, anticancer screening, docking studies and in silico ADME prediction of some β-carboline derivatives.

Design, synthesis, anticancer screening, docking studies and in silico ADME prediction of some β-carboline derivatives.

Journal: Future medicinal chemistry

Published: May 23, 2018

Synthesis, biological evaluation and molecular modeling of novel thienopyrimidinone and triazolothienopyrimidinone derivatives as dual anti-inflammatory antimicrobial agents.

Synthesis, biological evaluation and molecular modeling of novel thienopyrimidinone and triazolothienopyrimidinone derivatives as dual anti-inflammatory antimicrobial agents.

Journal: Bioorganic chemistry

Published: December 03, 2017

Synthesis, evaluation and modeling of some triazolothienopyrimidinones as anti-inflammatory and antimicrobial agents.

Synthesis, evaluation and modeling of some triazolothienopyrimidinones as anti-inflammatory and antimicrobial agents.

Journal: Future medicinal chemistry

Published: June 22, 2017

Showing 1-12 of 12

Last Updated: 09/26/2026