Malcolm G. Stevens

Nottingham, ENG NG72RD, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

Antitumour imidazotetrazines: past, present… and future?

Antitumour imidazotetrazines: past, present… and future?

Journal: RSC chemical biology

Published: May 25, 2023

Discovery of new imidazotetrazinones with potential to overcome tumor resistance.

Discovery of new imidazotetrazinones with potential to overcome tumor resistance.

Journal: European journal of medicinal chemistry

Published: April 13, 2023

In search of effective therapies to overcome resistance to Temozolomide in brain tumours.

In search of effective therapies to overcome resistance to Temozolomide in brain tumours.

Journal: Cancer drug resistance (Alhambra, Calif.)

Published: July 31, 2019

The antitumour activity of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole in human gastric cancer models is mediated by AhR signalling.

The antitumour activity of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole in human gastric cancer models is mediated by AhR signalling.

Journal: Journal of cellular and molecular medicine

Published: July 10, 2019

C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage.

C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage.

Journal: Frontiers in oncology

Published: March 09, 2019

Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells.

Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells.

Journal: Journal of cellular biochemistry

Published: November 16, 2017

Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position.

Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position.

Journal: MedChemComm

Published: November 01, 2017

Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines.

Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines.

Journal: Organic & biomolecular chemistry

Published: April 02, 2016

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery.

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery.

Journal: Bioorganic & medicinal chemistry

Published: July 24, 2015

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.

Journal: Journal of experimental & clinical cancer research : CR

Published: November 18, 2014

Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences.

Ligand selectivity in stabilising tandem parallel folded G-quadruplex motifs in human telomeric DNA sequences.

Journal: Chemical communications (Cambridge, England)

Published: October 24, 2014

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.

Journal: Journal of experimental & clinical cancer research : CR

Published: August 11, 2014

Showing 1-12 of 14

Last Updated: 09/26/2026