Malin L. Appell - Publications

Development and analytical validation of a targeted short-read next generation sequencing-based pharmacogenetic panel for comprehensive variant detection.

Journal: British journal of pharmacology

Published: September 19, 2025

Same, same, but different: exploring and comparing students' experiences of problem-based learning in a Swedish and a Kenyan medical education context.

Journal: Advances in health sciences education : theory and practice

Published: March 05, 2025

Response to azathioprine treatment in autoimmune hepatitis is dependent on glutathione transferase genotypes.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Published: June 25, 2024

Quantification of deoxythioguanosine in human DNA with LC-MS/MS, a marker for thiopurine therapy optimisation.

Journal: Analytical and bioanalytical chemistry

Published: May 31, 2024

No association between relapse hazard and thiopurine methyltransferase geno- or phenotypes in non-high risk acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study.

Journal: Cancer chemotherapy and pharmacology

Published: January 20, 2021

Pharmacogenetic studies of thiopurine methyltransferase genotype-phenotype concordance and effect of methotrexate on thiopurine metabolism.

Journal: Basic & clinical pharmacology & toxicology

Published: May 19, 2020

The Role of TPMT, ITPA, and NUDT15 Variants during Mercaptopurine Treatment of Swedish Pediatric Patients with Acute Lymphoblastic Leukemia.

Journal: The Journal of pediatrics

Published: February 26, 2019

Comprehensive study of thiopurine methyltransferase genotype, phenotype, and genotype-phenotype discrepancies in Sweden.

Journal: Biochemical pharmacology

Published: January 11, 2019

Role of TPMT and ITPA variants in mercaptopurine disposition.

Journal: Cancer chemotherapy and pharmacology

Published: October 10, 2017

One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability.

Journal: Scientific reports

Published: December 07, 2016

Interconnections between apoptotic and autophagic pathways during thiopurine-induced toxicity in cancer cells: the role of reactive oxygen species.

Journal: Oncotarget

Published: May 26, 2016

Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.

Journal: Clinical pharmacology and therapeutics

Published: September 03, 2015