Man R. Pan
Shanghai, China
Last Updated: 09/26/2026
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Found 27 publications
Site-Specific Apo AI Glycation Impairs HDL Function and Promotes Atherosclerosis in Diabetes.
Journal: Circulation
Published: August 25, 2026
Precision chemical synthesis of PEGylated IGF2 for potent and selective lysosomal degradation of transmembrane proteins.
Journal: Organic & biomolecular chemistry
Published: July 09, 2026
Conformation-specific Antibody Deciphers K27-linked Ubiquitination in Chaperone-Mediated Proteostasis.
Journal: bioRxiv : the preprint server for biology
Published: December 25, 2025
Targeted Protein Degradation by Repurposing Transmembrane E3 Ubiquitin Ligases.
Journal: Chembiochem : a European journal of chemical biology
Published: November 11, 2025
Unique gluing effect of ASXL1 K351 monoubiquitination stimulates the PR-DUB activity.
Journal: Nature chemical biology
Published: April 25, 2025
Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs.
Journal: Angewandte Chemie (International ed. in English)
Published: January 18, 2025
Allosteric activation of RNF20/RNF40-RAD6A-mediated H2BK120 monoubiquitylation by H2BS112 GlcNAcylation.
Journal: Nature chemical biology
Published: January 01, 2025
Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring ubiquitin to form K29/K48-branched polyubiquitination.
Journal: Nature communications
Published: November 19, 2024
Structural basis for E4 enzyme Ufd2-catalyzed K48/K29 branched ubiquitin chains.
Journal: Nature chemical biology
Published: November 13, 2024
Chemical Synthesis of Human Proteoforms and Application in Biomedicine.
Journal: ACS central science
Published: April 19, 2024
Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168.
Journal: Nature chemical biology
Published: January 01, 2024
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16.
Journal: Nature structural & molecular biology
Published: October 11, 2023
Last Updated: 09/26/2026