Manar S. Shafat

Norwich Research Park
Norwich, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 21 publications

AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival.

AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival.

Journal: Journal for immunotherapy of cancer

Published: July 27, 2023

Pembrolizumab for the treatment of progressive multifocal leukoencephalopathy following anti-CD19 CAR-T therapy: a case report.

Pembrolizumab for the treatment of progressive multifocal leukoencephalopathy following anti-CD19 CAR-T therapy: a case report.

Journal: EJHaem

Published: June 02, 2021

Multi-organ graft-versus-host disease after nivolumab for relapsed Hodgkin lymphoma: the role of plasma exchange.

Multi-organ graft-versus-host disease after nivolumab for relapsed Hodgkin lymphoma: the role of plasma exchange.

Journal: The Lancet. Haematology

Published: March 07, 2021

Synthesis of Carboxamide-Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia.

Synthesis of Carboxamide-Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia.

Journal: ChemMedChem

Published: September 22, 2020

A survey of cancer genome signatures identifies genes connected to distinct chromosomal instability phenotypes.

A survey of cancer genome signatures identifies genes connected to distinct chromosomal instability phenotypes.

Journal: The pharmacogenomics journal

Published: April 20, 2020

Cellular Therapeutic Approaches to Cytomegalovirus Infection Following Allogeneic Stem Cell Transplantation.

Cellular Therapeutic Approaches to Cytomegalovirus Infection Following Allogeneic Stem Cell Transplantation.

Journal: Frontiers in immunology

Published: April 08, 2020

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Journal: Blood

Published: April 14, 2018

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC.

Journal: Journal of hematology & oncology

Published: February 21, 2018

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia.

Journal: Oncogene

Published: August 03, 2017

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Journal: Nature medicine

Published: June 07, 2017

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST-Segment Elevation Myocardial Infarction.

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST-Segment Elevation Myocardial Infarction.

Journal: Journal of the American Heart Association

Published: May 05, 2017

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Journal: Nature medicine

Published: April 08, 2017

Showing 1-12 of 21

Last Updated: 09/26/2026