Manfred Lehner

St. Anna Kinderspital
Vienna, Austria

Last Updated: 09/26/2026

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Found 24 publications

Nucleotide-resolution mapping of regulatory elements via allelic readout of tiled base editing.

Nucleotide-resolution mapping of regulatory elements via allelic readout of tiled base editing.

Journal: Nature communications
Published: October 27, 2025

Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes.

Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes.

Journal: Science immunology
Published: October 17, 2025

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation.

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation.

Journal: Science advances
Published: September 04, 2024

Small molecule-regulated switches to provide functional control of CAR T cells within the patient.

Small molecule-regulated switches to provide functional control of CAR T cells within the patient.

Journal: Expert opinion on biological therapy
Published: June 29, 2024

Natural Killer Cell-Mediated Cytotoxicity Shapes the Clonal Evolution of B-cell Leukemia.

Natural Killer Cell-Mediated Cytotoxicity Shapes the Clonal Evolution of B-cell Leukemia.

Journal: Cancer immunology research
Published: February 22, 2024

The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif.

The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif.

Journal: Science signaling
Published: October 03, 2023

Solving the mystery of the FMC63-CD19 affinity.

Solving the mystery of the FMC63-CD19 affinity.

Journal: Scientific reports
Published: September 04, 2023

An engineering strategy to target activated EGFR with CAR T cells.

An engineering strategy to target activated EGFR with CAR T cells.

Journal: Cell reports methods
Published: August 31, 2023

Interrogating ligand-receptor interactions using highly sensitive cellular biosensors.

Interrogating ligand-receptor interactions using highly sensitive cellular biosensors.

Journal: Nature communications
Published: April 03, 2023

The frequency of differentiated CD3+CD27-CD28- T cells predicts response to CART cell therapy in diffuse large B-cell lymphoma.

The frequency of differentiated CD3+CD27-CD28- T cells predicts response to CART cell therapy in diffuse large B-cell lymphoma.

Journal: Frontiers in immunology
Published: July 27, 2022

Preclinical testing of CAR T cells in zebrafish xenografts.

Preclinical testing of CAR T cells in zebrafish xenografts.

Journal: Methods in cell biology
Published: February 14, 2022

PhosphoFlowSeq - A High-throughput Kinase Activity Assay for Screening Drug Resistance Mutations in EGFR.

PhosphoFlowSeq - A High-throughput Kinase Activity Assay for Screening Drug Resistance Mutations in EGFR.

Journal: Journal of molecular biology
Published: June 02, 2021
Showing 1-12 of 24

Last Updated: 09/26/2026