Mannix Messier-Auger

Sherbrooke, QC J1H5N4, Canada

Last Updated: 09/26/2026

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Found 28 publications

Tunable Biased Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Engineering and Allosteric Site Targeting.

Tunable Biased Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Engineering and Allosteric Site Targeting.

Journal: Journal of medicinal chemistry

Published: January 16, 2026

ArfGAP with Dual Pleckstrin Homology Domains 2 Promotes Hypertrophy of Cultured Neonatal Cardiomyocytes.

ArfGAP with Dual Pleckstrin Homology Domains 2 Promotes Hypertrophy of Cultured Neonatal Cardiomyocytes.

Journal: International journal of molecular sciences

Published: April 22, 2025

A Metabolically Stable Apelin-13 Analog Acting as a Potent ITo Potassium Current Blocker with Potential Benefits for Brugada Syndrome.

A Metabolically Stable Apelin-13 Analog Acting as a Potent ITo Potassium Current Blocker with Potential Benefits for Brugada Syndrome.

Journal: International journal of molecular sciences

Published: February 11, 2025

Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice.

Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice.

Journal: Science translational medicine

Published: March 20, 2024

Apelin prevents diabetes-induced poor collateral vessel formation and blood flow reperfusion in ischemic limb.

Apelin prevents diabetes-induced poor collateral vessel formation and blood flow reperfusion in ischemic limb.

Journal: Frontiers in cardiovascular medicine

Published: March 22, 2023

Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model.

Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model.

Journal: Journal of the American Heart Association

Published: February 08, 2023

Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects.

Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects.

Journal: Journal of medicinal chemistry

Published: January 04, 2022

Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation.

Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation.

Journal: International journal of molecular sciences

Published: November 08, 2021

Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake.

Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake.

Journal: Frontiers in pharmacology

Published: May 14, 2021

Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients.

Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients.

Journal: Scientific reports

Published: March 30, 2021

Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.

Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.

Journal: American journal of physiology. Heart and circulatory physiology

Published: February 26, 2021

Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.

Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.

Journal: Journal of medicinal chemistry

Published: February 01, 2021

Showing 1-12 of 28

Last Updated: 09/26/2026