Manu De Rycker
Dundee, SCT, United Kingdom
Last Updated: 09/26/2026
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Found 48 publications
Decoding efficacy and resistance space at a drug binding site.
Journal: Nature communications
Published: August 12, 2025
Target product profile and discovery and development path for novel cryptococcal disease treatments.
Target product profile and discovery and development path for novel cryptococcal disease treatments.
Journal: The Journal of infection
Published: May 30, 2025
Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein.
Journal: Molecular and biochemical parasitology
Published: April 01, 2025
Structure-activity relationships of 1,5-dihydro-2H-benzo[b][1,4]diazepine-2,4(3H)-diones as inhibitors of Trypanosoma cruzi.
Journal: RSC medicinal chemistry
Published: February 28, 2025
Trypanosoma cruzi cell atlas as a single-cell resource for understanding parasite population heterogeneity and differentiation.
Journal: Nature communications
Published: December 17, 2024
Identification of potent inhibitors of Leishmania donovani and Leishmania infantum chagasi, the causative agents of Old and New World visceral leishmaniasis.
Journal: Communications biology
Published: September 23, 2024
Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors.
Journal: The Journal of biological chemistry
Published: May 22, 2024
Validation of Trypanosoma cruzi inactivation techniques for laboratory use.
Journal: PloS one
Published: December 22, 2023
Short-course combination treatment for experimental chronic Chagas disease.
Journal: Science translational medicine
Published: December 13, 2023
Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
Journal: Journal of medicinal chemistry
Published: July 28, 2023
Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity.
Journal: PLoS neglected tropical diseases
Published: July 27, 2023
Last Updated: 09/26/2026