Manuel O. Jakob

Bern, BE, Switzerland

Last Updated: 09/26/2026

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Found 27 publications

A neuro-epithelial unit regulates immunohomeostasis at barrier surfaces.

A neuro-epithelial unit regulates immunohomeostasis at barrier surfaces.

Journal: Mucosal immunology

Published: April 07, 2026

Intestinal GAPs: neuro-epithelial-immune modules for liver protection.

Intestinal GAPs: neuro-epithelial-immune modules for liver protection.

Journal: Cell research

Published: October 16, 2025

Coordinated Interferon-γ/Tumor Necrosis Factor Axis Drives Selective Loss of Activated Enteric Glia in Inflammatory Bowel Diseases.

Coordinated Interferon-γ/Tumor Necrosis Factor Axis Drives Selective Loss of Activated Enteric Glia in Inflammatory Bowel Diseases.

Journal: Cellular and molecular gastroenterology and hepatology

Published: June 03, 2025

Distinguishing Features of ILC2s During Type 2 Immune Responses.

Distinguishing Features of ILC2s During Type 2 Immune Responses.

Journal: European journal of immunology

Published: May 11, 2025

Neuroepithelial VIP-VIPR1 interactions differentially control enteric type 1 and type 2 immunity.

Neuroepithelial VIP-VIPR1 interactions differentially control enteric type 1 and type 2 immunity.

Journal: Nature immunology

Published: April 10, 2025

Characterization of intestinal immune responses in generalized human and murine lipodystrophy.

Characterization of intestinal immune responses in generalized human and murine lipodystrophy.

Journal: The Journal of clinical investigation

Published: February 14, 2025

Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs.

Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage impeding type 2 immune programs.

Journal: Nature immunology

Published: September 21, 2024

A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation.

A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation.

Journal: Neuron

Published: June 06, 2024

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells.

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells.

Journal: Nature communications

Published: March 15, 2024

Predictors for surgical site infection in patients undergoing therapeutic or prophylactic intra-abdominal onlay mesh (IPOM) implantation in clean and contaminated surgical fields.

Predictors for surgical site infection in patients undergoing therapeutic or prophylactic intra-abdominal onlay mesh (IPOM) implantation in clean and contaminated surgical fields.

Journal: Surgical endoscopy

Published: March 07, 2023

ILC2 require cell-intrinsic ST2 signals to promote type 2 immune responses.

ILC2 require cell-intrinsic ST2 signals to promote type 2 immune responses.

Journal: Frontiers in immunology

Published: December 23, 2022

Hepatic blood flow regulation but not oxygen extraction capability is impaired in prolonged experimental abdominal sepsis.

Hepatic blood flow regulation but not oxygen extraction capability is impaired in prolonged experimental abdominal sepsis.

Journal: American journal of physiology. Gastrointestinal and liver physiology

Published: August 31, 2022

Showing 1-12 of 27

Last Updated: 09/26/2026