Manuel Portero-Otin

Department Of Crop And Forest Sciences
Lleida, CT 25198, Spain

Last Updated: 09/26/2026

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Found 143 publications

Pharmacological modulation with the LXR agonist T0901317 attenuates motor pathology in the SOD1G93A mouse model of ALS.

Pharmacological modulation with the LXR agonist T0901317 attenuates motor pathology in the SOD1G93A mouse model of ALS.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Published: May 28, 2026

Effects of aged black garlic (ABG10+®) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.

Effects of aged black garlic (ABG10+®) on lipoprotein subclass composition in Grade I hypertension: a randomized, triple-blind controlled trial with sex-stratified sequential allocation.

Journal: Frontiers in nutrition

Published: April 30, 2026

NRF2 deficit prevents pathologic Tau seeding and spreading in an induced tauopathy mouse model.

NRF2 deficit prevents pathologic Tau seeding and spreading in an induced tauopathy mouse model.

Journal: Redox biology

Published: January 11, 2026

Antisense oligonucleotides treatment uncovers differences in the modulation of dysregulated intracellular pathways in Spinal Muscular Atrophy motoneurons.

Antisense oligonucleotides treatment uncovers differences in the modulation of dysregulated intracellular pathways in Spinal Muscular Atrophy motoneurons.

Journal: Cell death & disease

Published: December 09, 2025

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival.

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival.

Journal: Brain pathology (Zurich, Switzerland)

Published: August 12, 2025

Mitochondrial lipidome's fatty acid profile and peroxidation index are programmed tissue-specific traits.

Mitochondrial lipidome's fatty acid profile and peroxidation index are programmed tissue-specific traits.

Journal: Redox biology

Published: July 18, 2025

Nuclear pore complex dysfunction drives TDP-43 pathology in ALS.

Nuclear pore complex dysfunction drives TDP-43 pathology in ALS.

Journal: Redox biology

Published: July 04, 2025

Genetic determinism of fatty acid composition in liver, muscle, backfat and plasma and its link to immunocompetence and performance in pigs.

Genetic determinism of fatty acid composition in liver, muscle, backfat and plasma and its link to immunocompetence and performance in pigs.

Journal: Scientific reports

Published: June 27, 2025

Mission cholesterol: Uncovering its hidden role in ALS neurodegeneration.

Mission cholesterol: Uncovering its hidden role in ALS neurodegeneration.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: June 05, 2025

Ether lipids and sphingolipids drive sex-specific human aging dynamics.

Ether lipids and sphingolipids drive sex-specific human aging dynamics.

Journal: Redox biology

Published: April 29, 2025

Exploring platelet metabolomics and fatty acid profiles for ALS prognosis and diagnosis.

Exploring platelet metabolomics and fatty acid profiles for ALS prognosis and diagnosis.

Journal: Scientific reports

Published: March 17, 2025

Non-enzymatic modification of aminophospholipids induces angiogenesis, inflammation, and insulin signaling dysregulation in human renal glomerular endothelial cells in vitro.

Non-enzymatic modification of aminophospholipids induces angiogenesis, inflammation, and insulin signaling dysregulation in human renal glomerular endothelial cells in vitro.

Journal: Free radical biology & medicine

Published: February 25, 2025

Showing 1-12 of 143

Last Updated: 09/26/2026