Manuel Puyol-Rodriguez

Madrid, MD, Spain

Last Updated: 09/26/2026

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Found 39 publications

A new graphene-based nanomaterial increases lipolysis and reduces body weight gain through integrin linked kinase (ILK).

A new graphene-based nanomaterial increases lipolysis and reduces body weight gain through integrin linked kinase (ILK).

Journal: Biomaterials science

Published: June 12, 2023

Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy.

Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy.

Journal: European journal of pharmacology

Published: October 31, 2022

The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo.

The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo.

Journal: Cell & bioscience

Published: September 07, 2021

A Computer-Driven Scaffold-Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2-a]quinoxaline Core.

A Computer-Driven Scaffold-Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2-a]quinoxaline Core.

Journal: ChemMedChem

Published: May 17, 2021

Pyrrolo[1,2-a]quinoxal-5-inium salts and 4,5-dihydropyrrolo[1,2-a]quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B.

Pyrrolo[1,2-a]quinoxal-5-inium salts and 4,5-dihydropyrrolo[1,2-a]quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B.

Journal: Bioorganic & medicinal chemistry

Published: April 01, 2021

Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with α-Parvin.

Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with α-Parvin.

Journal: ACS medicinal chemistry letters

Published: April 01, 2021

Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation.

Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation.

Journal: Experimental & molecular medicine

Published: March 22, 2021

Pyrrolo[1,2-a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B.

Pyrrolo[1,2-a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B.

Journal: ChemMedChem

Published: June 20, 2020

Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model.

Integrin Linked Kinase (ILK) Downregulation as an Early Event During the Development of Metabolic Alterations in a Short-Term High Fat Diet Mice Model.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Published: December 29, 2019

Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression.

Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: September 05, 2018

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold.

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold.

Journal: European journal of medicinal chemistry

Published: April 12, 2018

Contribution of uraemic toxins to the vascular fibrosis associated with chronic kidney disease.

Contribution of uraemic toxins to the vascular fibrosis associated with chronic kidney disease.

Journal: Nefrologia

Published: February 23, 2018

Showing 1-12 of 39

Last Updated: 09/26/2026