Manuela Hugle

Frankfurt Am Main, HE 60528, Germany

Last Updated: 09/26/2026

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Found 13 publications

Cell cycle arrest in mitosis promotes interferon-induced necroptosis.

Cell cycle arrest in mitosis promotes interferon-induced necroptosis.

Journal: Cell death and differentiation
Published: September 24, 2018

Identification of Smac mimetics as novel substrates for p-glycoprotein.

Identification of Smac mimetics as novel substrates for p-glycoprotein.

Journal: Cancer letters
Published: July 31, 2018

NRAS-Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3Kα.

NRAS-Mutated Rhabdomyosarcoma Cells Are Vulnerable to Mitochondrial Apoptosis Induced by Coinhibition of MEK and PI3Kα.

Journal: Cancer research
Published: June 12, 2017

Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines.

Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines.

Journal: Oncotarget
Published: January 12, 2017

Arsenic trioxide induces Noxa-dependent apoptosis in rhabdomyosarcoma cells and synergizes with antimicrotubule drugs.

Arsenic trioxide induces Noxa-dependent apoptosis in rhabdomyosarcoma cells and synergizes with antimicrotubule drugs.

Journal: Cancer letters
Published: May 03, 2016

Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells.

Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells.

Journal: Oncotarget
Published: August 07, 2015

Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells.

Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells.

Journal: International journal of cancer
Published: April 07, 2015

Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis.

Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis.

Journal: Oncotarget
Published: March 21, 2015

Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.

Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.

Journal: Cell death and differentiation
Published: February 17, 2015

Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma.

Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma.

Journal: Cancer letters
Published: November 05, 2014

Eribulin synergizes with Polo-like kinase 1 inhibitors to induce apoptosis in rhabdomyosarcoma.

Eribulin synergizes with Polo-like kinase 1 inhibitors to induce apoptosis in rhabdomyosarcoma.

Journal: Cancer letters
Published: July 21, 2014

Pan-mammalian target of rapamycin (mTOR) inhibitor AZD8055 primes rhabdomyosarcoma cells for ABT-737-induced apoptosis by down-regulating Mcl-1 protein.

Pan-mammalian target of rapamycin (mTOR) inhibitor AZD8055 primes rhabdomyosarcoma cells for ABT-737-induced apoptosis by down-regulating Mcl-1 protein.

Journal: The Journal of biological chemistry
Published: October 18, 2013
Showing 1-12 of 13

Last Updated: 09/26/2026