Marc C. Huisman
Amsterdam, NH, Netherlands
Last Updated: 09/26/2026
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Found 80 publications
A minimal physiologically-based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti-LAG-3 monoclonal antibody.
Journal: CPT: pharmacometrics & systems pharmacology
Published: June 28, 2024
Exploring the predictive potential of programmed death ligand 1 expression in healthy organs and lymph nodes as measured by 18F-BMS986-192 PET: pooled analysis of data from four solid tumor types.
Journal: Journal for immunotherapy of cancer
Published: May 28, 2024
First exploration of the on-treatment changes in tumor and organ uptake of a radiolabeled anti PD-L1 antibody during chemoradiotherapy in patients with non-small cell lung cancer using whole body PET.
Journal: Journal for immunotherapy of cancer
Published: January 03, 2024
The development process of 'fit-for-purpose' imaging biomarkers to characterize the tumor microenvironment.
Journal: Frontiers in medicine
Published: November 30, 2023
Non-specific irreversible 89Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using 89Zr-immuno-PET.
Journal: EJNMMI research
Published: November 29, 2023
89Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs.
Journal: Cancers
Published: September 15, 2023
How to obtain the image-derived blood concentration from 89Zr-immuno-PET scans.
Journal: EJNMMI physics
Published: July 03, 2023
Characterizing the Bone Marrow Environment in Advanced-Stage Myelofibrosis during Ruxolitinib Treatment Using PET/CT and MRI: A Pilot Study.
Journal: Tomography (Ann Arbor, Mich.)
Published: February 10, 2023
Clinical validation of translational antibody PBPK model using tissue distribution data generated with 89Zr-immuno-PET imaging.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: December 23, 2022
Validation of simplified uptake measures against dynamic Patlak Ki for quantification of lesional 89Zr-Immuno-PET antibody uptake.
Journal: European journal of nuclear medicine and molecular imaging
Published: November 10, 2022
89Zr-immuno-PET using the anti-LAG-3 tracer [89Zr]Zr-BI 754111: demonstrating target specific binding in NSCLC and HNSCC.
Journal: European journal of nuclear medicine and molecular imaging
Published: October 31, 2022
Last Updated: 09/26/2026