Marcel Spaargaren

Amsterdam, NH 1081HV, Netherlands

Last Updated: 09/26/2026

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Found 59 publications

Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma.

Targeting Wnt/β-catenin signaling enhances the efficacy of anti-CD38 immunotherapy in multiple myeloma.

Journal: Neoplasia (New York, N.Y.)
Published: September 10, 2025

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 11, 2025

Presentation of CXCL12γ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.

Presentation of CXCL12γ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells.

Journal: Blood advances
Published: July 31, 2024

DNA damage-induced p53 downregulates expression of RAG1 through a negative feedback loop involving miR-34a and FOXP1.

DNA damage-induced p53 downregulates expression of RAG1 through a negative feedback loop involving miR-34a and FOXP1.

Journal: The Journal of biological chemistry
Published: March 11, 2024

What's brewing for MALT1 in lymphoma?

What's brewing for MALT1 in lymphoma?

Journal: Blood
Published: December 07, 2023

The dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma.

The dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma.

Journal: Leukemia
Published: August 03, 2023

The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain.

The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain.

Journal: Blood cancer journal
Published: March 12, 2023

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas.

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas.

Journal: Blood cancer journal
Published: January 19, 2023

High karyotypic complexity is an independent prognostic factor in patients with CLL treated with venetoclax combinations.

High karyotypic complexity is an independent prognostic factor in patients with CLL treated with venetoclax combinations.

Journal: Blood
Published: January 17, 2023

Endothelial ICAM-1 Adhesome Recruits CD44 for Optimal Transcellular Migration of Human CTLs.

Endothelial ICAM-1 Adhesome Recruits CD44 for Optimal Transcellular Migration of Human CTLs.

Journal: Journal of immunology (Baltimore, Md. : 1950)
Published: October 18, 2022

Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies.

Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies.

Journal: Oncogenesis
Published: September 07, 2022

An Unbiased CRISPR-Cas9 Screening Method for the Identification of Positive and Negative Regulatory Proteins of Cell Adhesion.

An Unbiased CRISPR-Cas9 Screening Method for the Identification of Positive and Negative Regulatory Proteins of Cell Adhesion.

Journal: Bio-protocol
Published: June 30, 2022
Showing 1-12 of 59

Last Updated: 09/26/2026