Marcela Gronda

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 43 publications

Elevated mitochondrial protein import in acute myeloid leukemia increases reliance on mitochondrial protease LONP1.

Elevated mitochondrial protein import in acute myeloid leukemia increases reliance on mitochondrial protease LONP1.

Journal: The Journal of clinical investigation

Published: June 16, 2026

Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML.

Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML.

Journal: Leukemia

Published: December 10, 2025

Elevated mitochondrial protein import in acute myeloid leukemia increases reliance on mitochondrial protease LONP1.

Elevated mitochondrial protein import in acute myeloid leukemia increases reliance on mitochondrial protease LONP1.

Journal: The Journal of clinical investigation

Published: June 11, 2025

Mitochondrial RNA degradation regulates differentiation, stemness, and immune sensitivity in acute myeloid leukemia.

Mitochondrial RNA degradation regulates differentiation, stemness, and immune sensitivity in acute myeloid leukemia.

Journal: Nature communications

Published: May 05, 2025

Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.

Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 29, 2025

Acute myeloid leukemia drug-tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing.

Acute myeloid leukemia drug-tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing.

Journal: Haematologica

Published: June 05, 2024

Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase.

Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase.

Journal: Haematologica

Published: May 02, 2023

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.

Journal: Leukemia

Published: June 19, 2021

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.

Journal: Nature cell biology

Published: May 11, 2021

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production.

Journal: Blood

Published: September 09, 2020

Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.

Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.

Journal: Communications biology

Published: September 05, 2020

The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.

The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability.

Journal: Science translational medicine

Published: October 12, 2019

Showing 1-12 of 43

Last Updated: 09/26/2026