Marcella Rocchetti - Publications

Hypokalaemia and bradycardia unmask the loss-of-function phenotype of a Brugada Syndrome SCN5A mutation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Published: April 18, 2025

YAP1 reactivation in cardiomyocytes following ECM remodelling contributes to the development of contractile force and sarcomere maturation.

Journal: Cell death discovery

Published: February 04, 2025

Development of Small-molecule SERCA2a Stimulators: A Novel Class of Ino-lusitropic Agents.

Journal: European cardiology

Published: November 08, 2024

Selective SERCA2a activator as a candidate for chronic heart failure therapy.

Journal: Journal of translational medicine

Published: November 14, 2023

Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function.

Journal: The Journal of pharmacology and experimental therapeutics

Published: May 30, 2022

Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure.

Journal: Journal of medicinal chemistry

Published: May 17, 2022

A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes.

Journal: Communications biology

Published: May 05, 2022

Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging.

Journal: Theranostics

Published: January 10, 2022

Liraglutide preserves CD34+ stem cells from dysfunction Induced by high glucose exposure.

Journal: Cardiovascular diabetology

Published: November 18, 2021

Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation.

Journal: Stem cell research

Published: April 08, 2021

Structural and Electrophysiological Changes in a Model of Cardiotoxicity Induced by Anthracycline Combined With Trastuzumab.

Journal: Frontiers in physiology

Published: January 28, 2021

Targeting GRP receptor: Design, synthesis and preliminary biological characterization of new non-peptide antagonists of bombesin.

Journal: Bioorganic chemistry

Published: December 29, 2020