Margaryta Babych

Montreal, QC H2X3Y7, Canada

Last Updated: 09/26/2026

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Found 12 publications

Molecular Mechanisms of Islet Amyloid Polypeptide Aggregation: Towards Chemical Strategies to Prevent Amyloid Formation and to Design Non-Aggregating Peptide Therapeutics.

Molecular Mechanisms of Islet Amyloid Polypeptide Aggregation: Towards Chemical Strategies to Prevent Amyloid Formation and to Design Non-Aggregating Peptide Therapeutics.

Journal: International journal of molecular sciences

Published: January 30, 2026

Probing the Effect of α-Helical Stapling Strategies on the Inhibition of Peptide Aggregation and Amyloid Cytotoxicity.

Probing the Effect of α-Helical Stapling Strategies on the Inhibition of Peptide Aggregation and Amyloid Cytotoxicity.

Journal: ACS chemical biology

Published: January 05, 2026

Probing the relationships between self-assembly and the antimicrobial activity of amyloidogenic peptides: The islet amyloid polypeptide as a case study.

Probing the relationships between self-assembly and the antimicrobial activity of amyloidogenic peptides: The islet amyloid polypeptide as a case study.

Journal: Biochimica et biophysica acta. General subjects

Published: February 28, 2025

Probing the molecular determinants of the activation of toll-like receptor 2/6 by amyloid nanostructures through directed peptide self-assembly.

Probing the molecular determinants of the activation of toll-like receptor 2/6 by amyloid nanostructures through directed peptide self-assembly.

Journal: Soft matter

Published: September 03, 2024

Development of a novel fluorescence assay for studying lipid bilayer perturbation induced by amyloidogenic peptides using cell plasma membrane vesicles.

Development of a novel fluorescence assay for studying lipid bilayer perturbation induced by amyloidogenic peptides using cell plasma membrane vesicles.

Journal: Biochimica et biophysica acta. Biomembranes

Published: August 15, 2022

Contribution of the 12-17 hydrophobic region of islet amyloid polypeptide in self-assembly and cytotoxicity.

Contribution of the 12-17 hydrophobic region of islet amyloid polypeptide in self-assembly and cytotoxicity.

Journal: Frontiers in molecular biosciences

Published: August 11, 2022

Site-Specific Alkylation of the Islet Amyloid Polypeptide Accelerates Self-Assembly and Potentiates Perturbation of Lipid Membranes.

Site-Specific Alkylation of the Islet Amyloid Polypeptide Accelerates Self-Assembly and Potentiates Perturbation of Lipid Membranes.

Journal: Biochemistry

Published: July 15, 2021

Harnessing the Activation of Toll-Like Receptor 2/6 by Self-Assembled Cross-β Fibrils to Design Adjuvanted Nanovaccines.

Harnessing the Activation of Toll-Like Receptor 2/6 by Self-Assembled Cross-β Fibrils to Design Adjuvanted Nanovaccines.

Journal: Nanomaterials (Basel, Switzerland)

Published: September 18, 2020

Compartmentalized processing of catechols during mussel byssus fabrication determines the destiny of DOPA.

Compartmentalized processing of catechols during mussel byssus fabrication determines the destiny of DOPA.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 27, 2020

Identification of a novel TLR5 agonist derived from the P97 protein of Mycoplasma hyopneumoniae.

Identification of a novel TLR5 agonist derived from the P97 protein of Mycoplasma hyopneumoniae.

Journal: Immunobiology

Published: February 27, 2020

Guiding the Morphology of Amyloid Assemblies by Electrostatic Capping: from Polymorphic Twisted Fibrils to Uniform Nanorods.

Guiding the Morphology of Amyloid Assemblies by Electrostatic Capping: from Polymorphic Twisted Fibrils to Uniform Nanorods.

Journal: Small (Weinheim an der Bergstrasse, Germany)

Published: April 09, 2019

Engineering and evaluation of amyloid assemblies as a nanovaccine against the Chikungunya virus.

Engineering and evaluation of amyloid assemblies as a nanovaccine against the Chikungunya virus.

Journal: Nanoscale

Published: October 17, 2018

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Last Updated: 09/26/2026