Margot J. Lemieux

Edmonton, AB T6G2H7, Canada

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 94 publications

Identification of a Potent Pan-Coronaviral Main Protease Inhibitor.

Identification of a Potent Pan-Coronaviral Main Protease Inhibitor.

Journal: Journal of medicinal chemistry
Published: July 16, 2026

Distinct transport cycle and lipid regulation of a Mg2+-transporting P-type ATPase, MgtA.

Distinct transport cycle and lipid regulation of a Mg2+-transporting P-type ATPase, MgtA.

Journal: Research square
Published: May 18, 2026

Supercharging the calcium pump: Identification of an activation hotspot on SERCA by cryo-EM.

Supercharging the calcium pump: Identification of an activation hotspot on SERCA by cryo-EM.

Journal: bioRxiv : the preprint server for biology
Published: February 12, 2026

Structural and Functional Analysis of GGPPS Inhibition as a Therapeutic Mechanism for Acute Myeloid Leukemia (AML).

Structural and Functional Analysis of GGPPS Inhibition as a Therapeutic Mechanism for Acute Myeloid Leukemia (AML).

Journal: Research square
Published: January 09, 2026

Structural Elements of Dwarf Open Reading Frame Required for Activation of the Sarco-Endoplasmic Reticulum Calcium Pump.

Structural Elements of Dwarf Open Reading Frame Required for Activation of the Sarco-Endoplasmic Reticulum Calcium Pump.

Journal: Biochemistry
Published: September 05, 2025

Cofactor-Independent Amino Acid Epimerases with Catalytic Serines Instead of Cysteines.

Cofactor-Independent Amino Acid Epimerases with Catalytic Serines Instead of Cysteines.

Journal: Journal of molecular biology
Published: June 13, 2025

Production of human cathepsins using Expi293™ mammalian cell expression system for off-target activity of cysteine protease inhibitor screening.

Production of human cathepsins using Expi293™ mammalian cell expression system for off-target activity of cysteine protease inhibitor screening.

Journal: Protein science : a publication of the Protein Society
Published: May 02, 2025

Structural insights into the nirmatrelvir-resistant SARS-CoV-2 Mpro L50F/E166A/L167F triple mutant-inhibitor-complex reveal strategies for next generation coronaviral inhibitor design.

Structural insights into the nirmatrelvir-resistant SARS-CoV-2 Mpro L50F/E166A/L167F triple mutant-inhibitor-complex reveal strategies for next generation coronaviral inhibitor design.

Journal: RSC medicinal chemistry
Published: April 24, 2025

Structure and inhibition of diaminopimelic acid epimerase by slow-binding α-methyl amino acids.

Structure and inhibition of diaminopimelic acid epimerase by slow-binding α-methyl amino acids.

Journal: Protein science : a publication of the Protein Society
Published: March 07, 2025

Rhomboid protease GlpG regulates type 1 pili quality control and virulence in pathogenic E. coli.

Rhomboid protease GlpG regulates type 1 pili quality control and virulence in pathogenic E. coli.

Journal: Nature communications
Published: February 07, 2025

Transmembrane Parkinson's disease mutation of PINK1 leads to altered mitochondrial anchoring.

Transmembrane Parkinson's disease mutation of PINK1 leads to altered mitochondrial anchoring.

Journal: The Journal of biological chemistry
Published: November 08, 2024

Assessment of optimized FRET substrates as universal corona- and picornavirus main protease substrates for screening assays.

Assessment of optimized FRET substrates as universal corona- and picornavirus main protease substrates for screening assays.

Journal: RSC advances
Published: September 12, 2024
Showing 1-12 of 94

Last Updated: 09/26/2026