Maria A. Sortino

Catania, Italy

Last Updated: 09/26/2026

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Found 53 publications

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation-Energy Axis?

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation-Energy Axis?

Journal: Phytotherapy research : PTR

Published: March 09, 2026

Calcineurin inhibition mitigates activation of enteric glia in vitro and affects their crosstalk with macrophages.

Calcineurin inhibition mitigates activation of enteric glia in vitro and affects their crosstalk with macrophages.

Journal: Neurochemistry international

Published: December 23, 2025

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity.

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity.

Journal: ACS chemical neuroscience

Published: December 10, 2025

Hypoxia reverses the early anti-inflammatory microglial response to the β-amyloid peptide: mitochondrial involvement and beneficial roles of melatonin and naringenin.

Hypoxia reverses the early anti-inflammatory microglial response to the β-amyloid peptide: mitochondrial involvement and beneficial roles of melatonin and naringenin.

Journal: Journal of translational medicine

Published: April 17, 2025

Group II metabotropic glutamate receptors modulate blood brain barrier function: direct and indirect effect through astrocytes and microglia.

Group II metabotropic glutamate receptors modulate blood brain barrier function: direct and indirect effect through astrocytes and microglia.

Journal: European journal of pharmacology

Published: March 12, 2025

Cholesterol metabolites modulate ionotropic P2X4 and P2X7 receptor current in microglia cells.

Cholesterol metabolites modulate ionotropic P2X4 and P2X7 receptor current in microglia cells.

Journal: Neuropharmacology

Published: October 18, 2024

Preclinical and clinical study on type 3 metabotropic glutamate receptors in Parkinson's disease.

Preclinical and clinical study on type 3 metabotropic glutamate receptors in Parkinson's disease.

Journal: NPJ Parkinson's disease

Published: July 26, 2024

Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer's Disease.

Increased Heat Pain Tolerance but Hyperalgesia to Tonic Inflammatory Pain in the CRND8 Mouse Model of Alzheimer's Disease.

Journal: Journal of Alzheimer's disease : JAD

Published: September 24, 2023

Microglia and the Blood-Brain Barrier: An External Player in Acute and Chronic Neuroinflammatory Conditions.

Microglia and the Blood-Brain Barrier: An External Player in Acute and Chronic Neuroinflammatory Conditions.

Journal: International journal of molecular sciences

Published: April 27, 2023

Melatonin Activates Anti-Inflammatory Features in Microglia in a Multicellular Context: Evidence from Organotypic Brain Slices and HMC3 Cells.

Melatonin Activates Anti-Inflammatory Features in Microglia in a Multicellular Context: Evidence from Organotypic Brain Slices and HMC3 Cells.

Journal: Biomolecules

Published: January 30, 2023

Microglia Contributes to BAF-312 Effects on Blood-Brain Barrier Stability.

Microglia Contributes to BAF-312 Effects on Blood-Brain Barrier Stability.

Journal: Biomolecules

Published: August 03, 2022

Purinergic ionotropic P2X7 and metabotropic glutamate mGlu5 receptors crosstalk influences pro-inflammatory conditions in microglia.

Purinergic ionotropic P2X7 and metabotropic glutamate mGlu5 receptors crosstalk influences pro-inflammatory conditions in microglia.

Journal: European journal of pharmacology

Published: July 20, 2022

Showing 1-12 of 53

Last Updated: 09/26/2026