Maria Cabello-Osuna

Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

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Found 23 publications

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Journal: Journal of medicinal chemistry

Published: July 28, 2023

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.

Journal: Nature communications

Published: April 12, 2022

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Journal: European journal of medicinal chemistry

Published: February 15, 2022

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Journal: Journal of medicinal chemistry

Published: April 27, 2021

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity.

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity.

Journal: Journal of medicinal chemistry

Published: July 15, 2020

Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.

Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.

Journal: RSC medicinal chemistry

Published: June 12, 2020

Substituted Aminoacetamides as Novel Leads for Malaria Treatment.

Substituted Aminoacetamides as Novel Leads for Malaria Treatment.

Journal: ChemMedChem

Published: June 01, 2019

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 10, 2019

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: March 22, 2019

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

Journal: Journal of medicinal chemistry

Published: December 21, 2018

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).

Journal: ACS medicinal chemistry letters

Published: December 07, 2018

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

Journal: ACS infectious diseases

Published: March 10, 2018

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Last Updated: 09/26/2026