Maria Espelosin

Pamplona, NC, Spain

Last Updated: 09/26/2026

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Found 15 publications

Reprogramming lipid metabolism for cognitive restoration in Alzheimer's via PLA2G4E.

Reprogramming lipid metabolism for cognitive restoration in Alzheimer's via PLA2G4E.

Journal: Alzheimer's & dementia (New York, N. Y.)

Published: February 19, 2026

Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease.

Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease.

Journal: NPJ Parkinson's disease

Published: September 22, 2025

Loss of PLA2G4E compromises synaptic structure and cognitive outcomes in mice.

Loss of PLA2G4E compromises synaptic structure and cognitive outcomes in mice.

Journal: Life science alliance

Published: March 25, 2025

FKBP51 inhibition ameliorates neurodegeneration and motor dysfunction in the neuromelanin-SNCA mouse model of Parkinson's disease.

FKBP51 inhibition ameliorates neurodegeneration and motor dysfunction in the neuromelanin-SNCA mouse model of Parkinson's disease.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: August 07, 2024

Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles.

Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles.

Journal: Gene therapy

Published: May 16, 2024

Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells.

Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells.

Journal: Frontiers in immunology

Published: December 22, 2022

Docosahexaenoic Acid Ameliorates Contextual Fear Memory Deficits in the Tg2576 Alzheimer's Disease Mouse Model: Cellular and Molecular Correlates.

Docosahexaenoic Acid Ameliorates Contextual Fear Memory Deficits in the Tg2576 Alzheimer's Disease Mouse Model: Cellular and Molecular Correlates.

Journal: Pharmaceutics

Published: November 14, 2022

Amyloid-Driven Tau Accumulation on Mitochondria Potentially Leads to Cognitive Deterioration in Alzheimer's Disease.

Amyloid-Driven Tau Accumulation on Mitochondria Potentially Leads to Cognitive Deterioration in Alzheimer's Disease.

Journal: International journal of molecular sciences

Published: October 07, 2021

PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment.

PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment.

Journal: Progress in neurobiology

Published: January 16, 2020

Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles.

Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles.

Journal: ACS chemical neuroscience

Published: August 24, 2019

Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors.

Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors.

Journal: ACS chemical neuroscience

Published: December 12, 2018

Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy.

Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy.

Journal: Molecular therapy. Nucleic acids

Published: December 10, 2018

Showing 1-12 of 15

Last Updated: 09/26/2026