Maria K. Lie

Copenhagen, Denmark

Last Updated: 09/26/2026

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Found 11 publications

CaMKIIα hub ligands are unable to reverse known phenotypes in Angelman syndrome mice.

CaMKIIα hub ligands are unable to reverse known phenotypes in Angelman syndrome mice.

Journal: Basic & clinical pharmacology & toxicology

Published: September 05, 2024

Synthesis of γ-Aminobutyric Acid (GABA) Analogues Conformationally Restricted by Bicyclo[3.1.0]hexane/hexene or [4.1.0]Heptane/heptene Backbones as Potent Betaine/GABA Transporter Inhibitors.

Synthesis of γ-Aminobutyric Acid (GABA) Analogues Conformationally Restricted by Bicyclo[3.1.0]hexane/hexene or [4.1.0]Heptane/heptene Backbones as Potent Betaine/GABA Transporter Inhibitors.

Journal: Organic letters

Published: June 08, 2022

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1.

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1.

Journal: Frontiers in chemistry

Published: July 05, 2021

Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex.

Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex.

Journal: Glia

Published: March 04, 2020

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects.

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects.

Journal: Neurochemical research

Published: January 30, 2020

Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors.

Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors.

Journal: Scientific reports

Published: January 20, 2020

Development of Non-GAT1-Selective Inhibitors: Challenges and Achievements.

Development of Non-GAT1-Selective Inhibitors: Challenges and Achievements.

Journal: Advances in neurobiology

Published: August 23, 2017

Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke.

Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke.

Journal: Advances in neurobiology

Published: August 23, 2017

Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3.

Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3.

Journal: ACS chemical neuroscience

Published: July 09, 2015

Pharmacological identification of a guanidine-containing β-alanine analogue with low micromolar potency and selectivity for the betaine/GABA transporter 1 (BGT1).

Pharmacological identification of a guanidine-containing β-alanine analogue with low micromolar potency and selectivity for the betaine/GABA transporter 1 (BGT1).

Journal: Neurochemical research

Published: March 27, 2014

Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats.

Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats.

Journal: Reproductive biology

Published: January 10, 2013

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Last Updated: 09/26/2026