Maria L. Franco

Valencia, VC, Spain

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 10 publications

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.

Journal: eLife

Published: July 19, 2024

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.

Journal: bioRxiv : the preprint server for biology

Published: August 14, 2023

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75NTR signaling in the p75exonIII-KO mice.

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75NTR signaling in the p75exonIII-KO mice.

Journal: Frontiers in molecular neuroscience

Published: June 09, 2023

Structural basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB.

Structural basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB.

Journal: Nature communications

Published: June 07, 2023

Intrinsically disordered regions couple the ligand binding and kinase activation of Trk neurotrophin receptors.

Intrinsically disordered regions couple the ligand binding and kinase activation of Trk neurotrophin receptors.

Journal: iScience

Published: January 20, 2022

Identification of a guanine-specific pocket in the protein N of SARS-CoV-2.

Identification of a guanine-specific pocket in the protein N of SARS-CoV-2.

Journal: Communications biology

Published: January 11, 2022

Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation.

Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation.

Journal: The Journal of biological chemistry

Published: May 21, 2021

TrkA-mediated endocytosis of p75-CTF prevents cholinergic neuron death upon γ-secretase inhibition.

TrkA-mediated endocytosis of p75-CTF prevents cholinergic neuron death upon γ-secretase inhibition.

Journal: Life science alliance

Published: July 08, 2020

Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.

Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor.

Journal: The Journal of biological chemistry

Published: October 01, 2019

Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux.

Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux.

Journal: The Journal of biological chemistry

Published: February 18, 2016

Showing 1-10 of 10

Last Updated: 09/26/2026