Maria L. Introvigne

Modena, Italy

Last Updated: 09/26/2026

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Found 9 publications

Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists.

Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists.

Journal: Journal of medicinal chemistry

Published: October 22, 2025

Restoring cefepime activity against multidrug-resistant KPC-producing Klebsiella pneumoniae by combination with boronic acid inhibitors, MB076 and S02030.

Restoring cefepime activity against multidrug-resistant KPC-producing Klebsiella pneumoniae by combination with boronic acid inhibitors, MB076 and S02030.

Journal: Antimicrobial agents and chemotherapy

Published: January 28, 2025

α-Triazolylboronic Acids: A Novel Scaffold to Target FLT3 in AML.

α-Triazolylboronic Acids: A Novel Scaffold to Target FLT3 in AML.

Journal: ChemMedChem

Published: August 10, 2024

Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits Acinetobacter-Derived Cephalosporinase Variants with an Expanded-Substrate Spectrum.

Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits Acinetobacter-Derived Cephalosporinase Variants with an Expanded-Substrate Spectrum.

Journal: Journal of medicinal chemistry

Published: June 26, 2023

Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii.

Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii.

Journal: Antibiotics (Basel, Switzerland)

Published: February 28, 2023

Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses.

Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses.

Journal: Antimicrobial agents and chemotherapy

Published: January 05, 2023

Straightforward synthesis of chiral non-racemic α-boryl isocyanides.

Straightforward synthesis of chiral non-racemic α-boryl isocyanides.

Journal: Organic & biomolecular chemistry

Published: July 21, 2021

1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase.

1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase.

Journal: ACS infectious diseases

Published: June 06, 2020

α-Triazolylboronic Acids: A Promising Scaffold for Effective Inhibitors of KPCs.

α-Triazolylboronic Acids: A Promising Scaffold for Effective Inhibitors of KPCs.

Journal: ChemMedChem

Published: February 28, 2020

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Last Updated: 09/26/2026