Maria V. Sinegubova

Federal State Institution, , 60 Let Oktjabrja Pr T 7, Bld. 1
Moscow, MOW 117312, Russian Federation

Last Updated: 09/26/2026

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Found 11 publications

Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process.

Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: November 18, 2025

Genomic and Phenotypic Characterization of CHO 4BGD Cells with Quad Knockout and Overexpression of Two Housekeeping Genes That Allow for Metabolic Selection and Extended Fed-Batch Culturing.

Genomic and Phenotypic Characterization of CHO 4BGD Cells with Quad Knockout and Overexpression of Two Housekeeping Genes That Allow for Metabolic Selection and Extended Fed-Batch Culturing.

Journal: Cells
Published: March 13, 2025

Increased glycoprotein hormone yield in stably transfected CHO cells using human serum albumin signal peptide for beta-chains.

Increased glycoprotein hormone yield in stably transfected CHO cells using human serum albumin signal peptide for beta-chains.

Journal: PeerJ
Published: August 16, 2024

A highly specific aptamer for the SARS-CoV-2 spike protein from the authentic strain.

A highly specific aptamer for the SARS-CoV-2 spike protein from the authentic strain.

Journal: Organic & biomolecular chemistry
Published: July 08, 2024

Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides.

Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides.

Journal: Doklady. Biochemistry and biophysics
Published: October 09, 2023

Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins.

Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins.

Journal: PeerJ
Published: April 14, 2023

Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD.

Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD.

Journal: Diagnostics (Basel, Switzerland)
Published: December 16, 2021

Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur®) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency.

Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur®) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency.

Journal: Pharmaceutics
Published: November 29, 2021

Targeted Knockout of the dhfr, glul, bak1, and bax Genes by the Multiplex Genome Editing in CHO Cells.

Targeted Knockout of the dhfr, glul, bak1, and bax Genes by the Multiplex Genome Editing in CHO Cells.

Journal: Doklady. Biochemistry and biophysics
Published: November 01, 2021

Antigenic properties of the SARS-CoV-2 nucleoprotein are altered by the RNA admixture.

Antigenic properties of the SARS-CoV-2 nucleoprotein are altered by the RNA admixture.

Journal: PeerJ
Published: August 11, 2021

High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the EEF1A1-based plasmid vector.

High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the EEF1A1-based plasmid vector.

Journal: PloS one
Published: November 19, 2020
Showing 1-11 of 11

Last Updated: 09/26/2026