Marian Plochan-Hruska

Zurich, ZH, Switzerland

Last Updated: 09/26/2026

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Found 27 publications

Treatment of spinal injury muscle spasticity by spinal subpial AAV9-GAD65/VGAT delivery: An efficacy and safety study in rat, pig, and NHP.

Treatment of spinal injury muscle spasticity by spinal subpial AAV9-GAD65/VGAT delivery: An efficacy and safety study in rat, pig, and NHP.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: February 28, 2026

Blocking RAN translation without altering repeat RNAs rescues C9ORF72-related ALS and FTD phenotypes.

Blocking RAN translation without altering repeat RNAs rescues C9ORF72-related ALS and FTD phenotypes.

Journal: Science (New York, N.Y.)

Published: February 05, 2026

Gpnmb defines a phagocytic state of microglia linked to cell death in prion disease mouse model.

Gpnmb defines a phagocytic state of microglia linked to cell death in prion disease mouse model.

Journal: Nature communications

Published: August 19, 2025

Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.

Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures.

Journal: Neuron

Published: July 18, 2024

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 01, 2022

An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.

An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.

Journal: The EMBO journal

Published: August 10, 2022

Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.

Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.

Journal: The EMBO journal

Published: May 20, 2022

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.

Journal: Nature

Published: September 28, 2021

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.

Journal: EMBO molecular medicine

Published: June 18, 2021

Targeted mass spectrometry for monitoring of neural differentiation.

Targeted mass spectrometry for monitoring of neural differentiation.

Journal: Biology open

Published: March 26, 2021

Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.

Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.

Journal: Cell reports

Published: August 10, 2020

Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS.

Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS.

Journal: Nature communications

Published: May 25, 2020

Showing 1-12 of 27

Last Updated: 09/26/2026