Marianne Kjalke

Novo Nordisk Park
Malov, Denmark

Last Updated: 09/26/2026

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Found 15 publications

Investigation of the Suitability of the ROTEM Assay to Measure Coagulation Potential in Blood From Patients on Concizumab Prophylaxis.

Investigation of the Suitability of the ROTEM Assay to Measure Coagulation Potential in Blood From Patients on Concizumab Prophylaxis.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: June 20, 2025

Examining downstream effects of concizumab in hemophilia A with a mathematical modeling approach.

Examining downstream effects of concizumab in hemophilia A with a mathematical modeling approach.

Journal: Journal of thrombosis and haemostasis : JTH

Published: August 15, 2024

Minimal interference of concizumab with standard clinical coagulation laboratory assays - An in vitro study.

Minimal interference of concizumab with standard clinical coagulation laboratory assays - An in vitro study.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: March 27, 2024

Concizumab improves clot formation in hemophilia A under flow.

Concizumab improves clot formation in hemophilia A under flow.

Journal: Journal of thrombosis and haemostasis : JTH

Published: November 02, 2023

A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.

A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.

Journal: Journal of thrombosis and haemostasis : JTH

Published: June 29, 2021

Thrombin generation potential in the presence of concizumab and rFVIIa, APCC, rFVIII, or rFIX: In vitro and ex vivo analyses.

Thrombin generation potential in the presence of concizumab and rFVIIa, APCC, rFVIII, or rFIX: In vitro and ex vivo analyses.

Journal: Journal of thrombosis and haemostasis : JTH

Published: December 09, 2020

An overview of turoctocog alfa pegol (N8-GP; ESPEROCT® ) assay performance: Implications for postadministration monitoring.

An overview of turoctocog alfa pegol (N8-GP; ESPEROCT® ) assay performance: Implications for postadministration monitoring.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: June 14, 2019

Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets.

Enhanced potency of recombinant factor VIIa with increased affinity to activated platelets.

Journal: Journal of thrombosis and haemostasis : JTH

Published: February 26, 2019

Factor VIII with a 237 amino acid B-domain has an extended half-life in F8-knockout mice.

Factor VIII with a 237 amino acid B-domain has an extended half-life in F8-knockout mice.

Journal: Journal of thrombosis and haemostasis : JTH

Published: April 12, 2018

Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8-GP) and development of a human pharmacokinetic prediction model.

Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8-GP) and development of a human pharmacokinetic prediction model.

Journal: Journal of thrombosis and haemostasis : JTH

Published: December 06, 2017

High-affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats.

High-affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats.

Journal: Journal of thrombosis and haemostasis : JTH

Published: January 12, 2016

Factor VIII chromogenic assays can be used for potency labeling and postadministration monitoring of N8-GP.

Factor VIII chromogenic assays can be used for potency labeling and postadministration monitoring of N8-GP.

Journal: Journal of thrombosis and haemostasis : JTH

Published: November 18, 2015

Showing 1-12 of 15

Last Updated: 09/26/2026