Marie-pierre Pruniaux

Sanofi R&D, 1 Avenue Pierre Brossolette
Chilly, 91385, France

Last Updated: 09/26/2026

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Found 10 publications

Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab.

Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab.

Journal: JACC. Basic to translational science

Published: December 26, 2019

Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy.

Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy.

Journal: Cardiovascular research

Published: June 15, 2018

Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols.

Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols.

Journal: International journal of molecular sciences

Published: April 20, 2017

Synthesis and multiparametric evaluation of thiadiazoles and oxadiazoles as diacylglycerol acyltransferase type 1 inhibitors.

Synthesis and multiparametric evaluation of thiadiazoles and oxadiazoles as diacylglycerol acyltransferase type 1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: October 02, 2015

Synthesis, characterization, and biological assessment of the four stereoisomers of the H(3) receptor antagonist 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide.

Synthesis, characterization, and biological assessment of the four stereoisomers of the H(3) receptor antagonist 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide.

Journal: Bioorganic & medicinal chemistry letters

Published: April 04, 2013

Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).

Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).

Journal: Bioorganic & medicinal chemistry letters

Published: January 23, 2013

Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).

Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).

Journal: Bioorganic & medicinal chemistry letters

Published: January 23, 2013

Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D.

Discovery of SAR184841, a potent and long-lasting inhibitor of 11β-hydroxysteroid dehydrogenase type 1, active in a physiopathological animal model of T2D.

Journal: Bioorganic & medicinal chemistry letters

Published: November 14, 2012

SAR110894, a potent histamine H₃-receptor antagonist, displays procognitive effects in rodents.

SAR110894, a potent histamine H₃-receptor antagonist, displays procognitive effects in rodents.

Journal: Pharmacology, biochemistry, and behavior

Published: February 27, 2012

Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1.

Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1.

Journal: Bioorganic & medicinal chemistry letters

Published: December 16, 2011

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Last Updated: 09/26/2026