Marien C. Houtman
Utrecht, UT, Netherlands
Last Updated: 09/26/2026
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Found 22 publications
Exploring the Cell Biological and Functional Effects of the First Disease Associated KCC1 Genetic Variant.
Journal: Journal of cellular physiology
Published: May 12, 2025
Arrhythmia Inducibility in the CAVB Dog Model, A Critical Analysis on Underlying Factors.
Journal: Cardiovascular toxicology
Published: March 31, 2025
Development of new Kir2.1 channel openers from propafenone analogues.
Journal: British journal of pharmacology
Published: March 20, 2024
Development of IKATP Ion Channel Blockers Targeting Sulfonylurea Resistant Mutant KIR6.2 Based Channels for Treating DEND Syndrome.
Journal: Frontiers in pharmacology
Published: November 12, 2021
LUF7244 plus Dofetilide Rescues Aberrant Kv11.1 Trafficking and Produces Functional IKv11.1.
Journal: Molecular pharmacology
Published: October 29, 2019
Identification of a PEST Sequence in Vertebrate KIR2.1 That Modifies Rectification.
Journal: Frontiers in physiology
Published: April 26, 2019
Glibenclamide and HMR1098 normalize Cantú syndrome-associated gain-of-function currents.
Journal: Journal of cellular and molecular medicine
Published: February 04, 2019
Computational Identification of Novel Kir6 Channel Inhibitors.
Journal: Frontiers in pharmacology
Published: February 04, 2019
LUF7244, an allosteric modulator/activator of Kv 11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model.
Journal: British journal of pharmacology
Published: November 27, 2018
Istaroxime, a positive inotropic agent devoid of proarrhythmic properties in sensitive chronic atrioventricular block dogs.
Journal: Pharmacological research
Published: January 18, 2018
Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.
Journal: British journal of pharmacology
Published: August 29, 2017
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo.
Journal: Pharmacological research
Published: August 24, 2017
Last Updated: 09/26/2026