Marina Makrecka-Kuka

Dzirciema Str. 16
Riga, RIX 1007, Latvia

Last Updated: 09/26/2026

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Found 51 publications

Exploiting PKM2-PARP1 dependency: Isoselenazolium-olaparib conjugates achieve multimodal PKM2 suppression.

Exploiting PKM2-PARP1 dependency: Isoselenazolium-olaparib conjugates achieve multimodal PKM2 suppression.

Journal: Bioorganic chemistry

Published: March 18, 2026

Gentamicin triggers fatty acid oxidation-dependent mitochondrial ROS, driving greater nephrotoxicity than apramycin and other aminoglycosides.

Gentamicin triggers fatty acid oxidation-dependent mitochondrial ROS, driving greater nephrotoxicity than apramycin and other aminoglycosides.

Journal: Free radical biology & medicine

Published: December 10, 2025

Development of Mitochondria-Targeted PARP Inhibitors.

Development of Mitochondria-Targeted PARP Inhibitors.

Journal: Biomolecules

Published: October 29, 2025

EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.

EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.

Journal: BioFactors (Oxford, England)

Published: November 26, 2024

Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models.

Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: July 31, 2024

Age-dependent changes in visceral adiposity are associated with decreased plasma levels of DHEA-S in sigma-1 receptor knockout male mice.

Age-dependent changes in visceral adiposity are associated with decreased plasma levels of DHEA-S in sigma-1 receptor knockout male mice.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids

Published: June 12, 2024

Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.

Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.

Journal: Journal of medicinal chemistry

Published: June 04, 2024

Editorial: Lipotoxicity, mitotoxicity, and drug targets.

Editorial: Lipotoxicity, mitotoxicity, and drug targets.

Journal: Frontiers in endocrinology

Published: June 23, 2023

Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors.

Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors.

Journal: European journal of medicinal chemistry

Published: April 16, 2023

Impact of the m.13513G>A Variant on the Functions of the OXPHOS System and Cell Retrograde Signaling.

Impact of the m.13513G>A Variant on the Functions of the OXPHOS System and Cell Retrograde Signaling.

Journal: Current issues in molecular biology

Published: December 23, 2022

Olaparib Conjugates with Selenopheno[3,2-c]quinolinone Inhibit PARP1 and Reverse ABCB1-Related Multidrug Resistance.

Olaparib Conjugates with Selenopheno[3,2-c]quinolinone Inhibit PARP1 and Reverse ABCB1-Related Multidrug Resistance.

Journal: Pharmaceutics

Published: October 01, 2022

SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function.

SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function.

Journal: Neurobiology of disease

Published: September 23, 2022

Showing 1-12 of 51

Last Updated: 09/26/2026