Mario Mezler

Ludwigshafen Am Rhein, RP 67061, Germany

Last Updated: 09/26/2026

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Found 29 publications

Oleic acid-based formulation enables drug delivery of bRo5 compounds through intestinal lymphatic absorption.

Oleic acid-based formulation enables drug delivery of bRo5 compounds through intestinal lymphatic absorption.

Journal: International journal of pharmaceutics

Published: January 13, 2026

Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles.

Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles.

Journal: Journal of medicinal chemistry

Published: November 22, 2025

Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs.

Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs.

Journal: Cell reports methods

Published: June 02, 2025

Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis.

Anti-pyroglutamate-3 Aβ immunotherapy engages microglia and inhibits amyloid accumulation in transgenic mouse models of Aβ amyloidosis.

Journal: Acta neuropathologica

Published: February 05, 2025

Macrocyclization as a Strategy for Kinetic Solubility Improvement: A Comparative Analysis of Matched Molecular Pairs.

Macrocyclization as a Strategy for Kinetic Solubility Improvement: A Comparative Analysis of Matched Molecular Pairs.

Journal: Journal of medicinal chemistry

Published: January 22, 2025

IQ-MPS Affiliate perspectives on blood-brain barrier microphysiological systems: Progress and challenges ahead.

IQ-MPS Affiliate perspectives on blood-brain barrier microphysiological systems: Progress and challenges ahead.

Journal: ALTEX

Published: November 22, 2024

Conquering the beyond Rule of Five Space with an Optimized High-Throughput Caco-2 Assay to Close Gaps in Absorption Prediction.

Conquering the beyond Rule of Five Space with an Optimized High-Throughput Caco-2 Assay to Close Gaps in Absorption Prediction.

Journal: Pharmaceutics

Published: May 13, 2024

Challenges in Permeability Assessment for Oral Drug Product Development.

Challenges in Permeability Assessment for Oral Drug Product Development.

Journal: Pharmaceutics

Published: July 10, 2023

Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.

Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: May 16, 2023

Correction: Improvement of Workfows and Assay Reproducibility by The Introduction of "Assay-Ready" Culturing of MDCK Cells for Transport Studie.

Correction: Improvement of Workfows and Assay Reproducibility by The Introduction of "Assay-Ready" Culturing of MDCK Cells for Transport Studie.

Journal: Pharmaceutical research

Published: April 18, 2023

Novel Developments to Enable Treatment of CNS Diseases with Targeted Drug Delivery.

Novel Developments to Enable Treatment of CNS Diseases with Targeted Drug Delivery.

Journal: Pharmaceutics

Published: December 21, 2022

Improvement of Workflows and Assay Reproducibility by The Introduction of "Assay-Ready" Culturing of MDCK Cells for Transport Studies.

Improvement of Workflows and Assay Reproducibility by The Introduction of "Assay-Ready" Culturing of MDCK Cells for Transport Studies.

Journal: Pharmaceutical research

Published: October 19, 2022

Showing 1-12 of 29

Last Updated: 09/26/2026