Mark F. Van Delft
Melbourne, VIC, Australia
Last Updated: 09/26/2026
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Found 22 publications
Differential regulation of BAX and BAK apoptotic activity revealed by small molecules.
Journal: Science advances
Published: March 05, 2025
Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins.
Journal: Cell death and differentiation
Published: July 05, 2024
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis.
Journal: PLoS biology
Published: December 23, 2023
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase.
Journal: The Biochemical journal
Published: February 09, 2023
Mitochondrial E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins.
Journal: Cell death and differentiation
Published: May 03, 2022
Too much death can kill you: inhibiting intrinsic apoptosis to treat disease.
Journal: The EMBO journal
Published: February 02, 2021
Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the Pathway.
Journal: ACS chemical biology
Published: September 09, 2020
The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL.
Journal: Cell death & disease
Published: August 24, 2020
MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex.
Journal: Cell death and differentiation
Published: July 03, 2019
Last Updated: 09/26/2026