Last Updated: 09/26/2026
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Found 8 publications
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's Disease.
Journal: Journal of medicinal chemistry
Published: July 11, 2022
Biomarker Assay Validation by Mass Spectrometry.
Journal: The AAPS journal
Published: February 14, 2022
Structure-Based Exploration of Selectivity for ATM Inhibitors in Huntington's Disease.
Journal: Journal of medicinal chemistry
Published: March 30, 2021
Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System.
Journal: Cells
Published: March 12, 2020
Application of an in Vitro Blood-Brain Barrier Model in the Selection of Experimental Drug Candidates for the Treatment of Huntington's Disease.
Journal: Molecular pharmaceutics
Published: March 28, 2019
Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington's Disease Models.
Journal: Journal of medicinal chemistry
Published: March 07, 2019
Validation of a method for the determination of AMG 579 in cerebrospinal fluid with a focus on sample collection procedures for clinical trials.
Journal: Journal of pharmaceutical and biomedical analysis
Published: January 20, 2015
Bioanalytical method validation: concepts, expectations and challenges in small molecule and macromolecule--a report of PITTCON 2013 symposium.
Journal: The AAPS journal
Published: February 06, 2014
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Last Updated: 09/26/2026