Mark L. Smythe

Brisbane, QLD 4072, Australia

Last Updated: 09/26/2026

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Found 8 publications

Pharmacology and macrophage modulation of HPGDS inhibitor PK007 demonstrate reduced disease severity in DMD-affected muscles of the mdx mouse model.

Pharmacology and macrophage modulation of HPGDS inhibitor PK007 demonstrate reduced disease severity in DMD-affected muscles of the mdx mouse model.

Journal: Skeletal muscle
Published: November 29, 2024

Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets.

Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets.

Journal: Current drug targets
Published: April 29, 2024

Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.

Dual therapy with corticosteroid ablates the beneficial effect of DP2 antagonism in chronic experimental asthma.

Journal: Nature communications
Published: November 26, 2023

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction.

Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction.

Journal: European heart journal
Published: April 08, 2023

Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD mdx Model Mice.

Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD mdx Model Mice.

Journal: Life (Basel, Switzerland)
Published: July 16, 2021

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production.

Journal: Science translational medicine
Published: June 05, 2017

Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23.

Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23.

Journal: BMC bioinformatics
Published: August 16, 2016

Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo.

Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo.

Journal: PloS one
Published: June 26, 2015
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Last Updated: 09/26/2026