Mark M. Iles

Leeds, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 82 publications

Investigating the repurposing potential of immune checkpoint inhibition for cancer treatment using Mendelian randomisation.

Investigating the repurposing potential of immune checkpoint inhibition for cancer treatment using Mendelian randomisation.

Journal: Research square
Published: August 20, 2026

Periodontal diseases and all-cause dementia risk: Genetic instrument analyses in half a million UK Biobank participants.

Periodontal diseases and all-cause dementia risk: Genetic instrument analyses in half a million UK Biobank participants.

Journal: Journal of Alzheimer's disease : JAD
Published: May 21, 2026

Functional characterization of the 9q34.13 locus identifies RAPGEF1 as modulating risk for melanoma and nevi via RAS activation.

Functional characterization of the 9q34.13 locus identifies RAPGEF1 as modulating risk for melanoma and nevi via RAS activation.

Journal: bioRxiv : the preprint server for biology
Published: May 08, 2026

Genetic biomarkers of clinical manifestations in giant cell arteritis define distinct patient subgroups.

Genetic biomarkers of clinical manifestations in giant cell arteritis define distinct patient subgroups.

Journal: Annals of the rheumatic diseases
Published: March 25, 2026

Integrative screening identifies functional variants and VNTRs underlying GWAS signals at the 5p15.33 multi-cancer susceptibility locus.

Integrative screening identifies functional variants and VNTRs underlying GWAS signals at the 5p15.33 multi-cancer susceptibility locus.

Journal: medRxiv : the preprint server for health sciences
Published: March 23, 2026

Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8.

Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8.

Journal: bioRxiv : the preprint server for biology
Published: January 16, 2026

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.

Journal: medRxiv : the preprint server for health sciences
Published: October 01, 2025

Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types.

Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types.

Journal: bioRxiv : the preprint server for biology
Published: August 06, 2025

Correction to: Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data.

Correction to: Genetic risk factors for periodontitis: a genome-wide association study using UK Biobank data.

Journal: Clinical oral investigations
Published: March 20, 2025

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.

Journal: Nature communications
Published: February 20, 2025

Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of cis-regulation.

Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of cis-regulation.

Journal: medRxiv : the preprint server for health sciences
Published: January 13, 2025

Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets.

Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets.

Journal: American journal of human genetics
Published: November 12, 2024
Showing 1-12 of 82

Last Updated: 09/26/2026