Mark S. Searle

University Park
Nottingham, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 33 publications

An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.

An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.

Journal: The Journal of biological chemistry
Published: October 05, 2021

Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.

Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.

Journal: Blood
Published: January 09, 2020

G-quadruplex ligands mediate downregulation of DUX4 expression.

G-quadruplex ligands mediate downregulation of DUX4 expression.

Journal: Nucleic acids research
Published: January 22, 2019

DNA replication initiation in Bacillus subtilis: structural and functional characterization of the essential DnaA-DnaD interaction.

DNA replication initiation in Bacillus subtilis: structural and functional characterization of the essential DnaA-DnaD interaction.

Journal: Nucleic acids research
Published: October 19, 2018

Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib.

Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib.

Journal: Blood advances
Published: October 05, 2018

Method for the Purification of Endogenous Unanchored Polyubiquitin Chains.

Method for the Purification of Endogenous Unanchored Polyubiquitin Chains.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: September 11, 2016

ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling.

ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling.

Journal: Molecular and cellular neurosciences
Published: May 12, 2016

Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.

Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD.

Journal: Autophagy
Published: May 10, 2016

SilE is an intrinsically disordered periplasmic "molecular sponge" involved in bacterial silver resistance.

SilE is an intrinsically disordered periplasmic "molecular sponge" involved in bacterial silver resistance.

Journal: Molecular microbiology
Published: April 15, 2016

Correction: Enantiopure titanocene complexes--direct evidence for paraptosis in cancer cells.

Correction: Enantiopure titanocene complexes--direct evidence for paraptosis in cancer cells.

Journal: Metallomics : integrated biometal science
Published: February 06, 2016

Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin.

Mass spectrometry insights into a tandem ubiquitin-binding domain hybrid engineered for the selective recognition of unanchored polyubiquitin.

Journal: Proteomics
Published: February 05, 2016

Enantiopure titanocene complexes--direct evidence for paraptosis in cancer cells.

Enantiopure titanocene complexes--direct evidence for paraptosis in cancer cells.

Journal: Metallomics : integrated biometal science
Published: January 26, 2016
Showing 1-12 of 33

Last Updated: 09/26/2026