Marketa J. Zvelebil
London, ENG SW36JB, United Kingdom
Last Updated: 09/26/2026
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Found 54 publications
Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders.
Journal: Journal of medicinal chemistry
Published: October 26, 2018
5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology.
Journal: Journal of medicinal chemistry
Published: August 23, 2017
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Journal: Nature communications
Published: August 05, 2016
Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer.
Journal: Breast cancer research : BCR
Published: March 03, 2016
Mouse mammary stem cells express prognostic markers for triple-negative breast cancer.
Journal: Breast cancer research : BCR
Published: September 30, 2014
Effect of aromatase inhibition on functional gene modules in estrogen receptor-positive breast cancer and their relationship with antiproliferative response.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: March 18, 2014
Deriving a mutation index of carcinogenicity using protein structure and protein interfaces.
Journal: PloS one
Published: July 22, 2013
ROCK: a resource for integrative breast cancer data analysis.
Journal: Breast cancer research and treatment
Published: March 28, 2013
Normalized mean glandular dose computation from mammography using GATE: a validation study.
Journal: Physics in medicine and biology
Published: March 12, 2013
Neuregulin 3 and erbb signalling networks in embryonic mammary gland development.
Journal: Journal of mammary gland biology and neoplasia
Published: January 21, 2013
Last Updated: 09/26/2026