Marketa Smidkova

Prague, PR 16610, Czech Republic

Last Updated: 09/26/2026

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Found 15 publications

Fluorescence-based assay for rapid screening of GABAA receptor modulating steroid antagonists (GAMSA).

Fluorescence-based assay for rapid screening of GABAA receptor modulating steroid antagonists (GAMSA).

Journal: Analytical biochemistry

Published: July 10, 2025

Fluorescence-Based HTS Assays for Ion Channel Modulation in Drug Discovery Pipelines.

Fluorescence-Based HTS Assays for Ion Channel Modulation in Drug Discovery Pipelines.

Journal: ChemMedChem

Published: May 20, 2024

Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.

Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.

Journal: Journal of medicinal chemistry

Published: May 03, 2023

Identification of N-methyl-D-aspartate receptor antagonists using the rat postnatal mixed cortical and hippocampal neurons.

Identification of N-methyl-D-aspartate receptor antagonists using the rat postnatal mixed cortical and hippocampal neurons.

Journal: European journal of pharmacology

Published: March 08, 2022

Could 5'-N and S ProTide analogues work as prodrugs of antiviral agents?

Could 5'-N and S ProTide analogues work as prodrugs of antiviral agents?

Journal: Bioorganic & medicinal chemistry letters

Published: September 29, 2019

Screening of novel 3α5β-neurosteroids for neuroprotective activity against glutamate- or NMDA-induced excitotoxicity.

Screening of novel 3α5β-neurosteroids for neuroprotective activity against glutamate- or NMDA-induced excitotoxicity.

Journal: The Journal of steroid biochemistry and molecular biology

Published: January 16, 2019

Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.

Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif.

Journal: Frontiers in pharmacology

Published: June 21, 2018

Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.

Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.

Journal: ChemMedChem

Published: May 17, 2018

Synthesis of α-Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases.

Synthesis of α-Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases.

Journal: ChemMedChem

Published: November 15, 2017

Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.

Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.

Journal: ChemMedChem

Published: August 25, 2016

Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors.

Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors.

Journal: Steroids

Published: April 25, 2016

Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus.

Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus.

Journal: Antiviral research

Published: February 10, 2016

Showing 1-12 of 15

Last Updated: 09/26/2026