Marlene S. Santos

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 22 publications

Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP).

Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP).

Journal: Critical care medicine

Published: May 08, 2026

Assessing the quality of consent discussions in intensive care unit research: A scoping review of outcome measures.

Assessing the quality of consent discussions in intensive care unit research: A scoping review of outcome measures.

Journal: Journal of critical care

Published: January 14, 2026

Intermediate dose heparin thromboprophylaxis among critically ill patients with COVID-19: a randomized clinical trial.

Intermediate dose heparin thromboprophylaxis among critically ill patients with COVID-19: a randomized clinical trial.

Journal: Journal of thrombosis and haemostasis : JTH

Published: October 10, 2025

Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation.

Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation.

Journal: The New England journal of medicine

Published: June 13, 2025

Coenrollment of critically ill patients in PROSPECT: characteristics and association with treatment efficacy and safety.

Coenrollment of critically ill patients in PROSPECT: characteristics and association with treatment efficacy and safety.

Journal: Trials

Published: May 18, 2025

Co-designing and pilot-testing an infographic to support the consent process in an adaptive platform trial for adults in ICU with community-acquired pneumonia or COVID-19: a mixed methods study within a trial (SWAT).

Co-designing and pilot-testing an infographic to support the consent process in an adaptive platform trial for adults in ICU with community-acquired pneumonia or COVID-19: a mixed methods study within a trial (SWAT).

Journal: Research involvement and engagement

Published: December 16, 2024

Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial.

Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial.

Journal: Thorax

Published: September 19, 2024

Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve stimulation: STIMIT ACTIVATOR 1 pivotal trial.

Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve stimulation: STIMIT ACTIVATOR 1 pivotal trial.

Journal: Trials

Published: April 19, 2024

Simvastatin in Critically Ill Patients with Covid-19.

Simvastatin in Critically Ill Patients with Covid-19.

Journal: The New England journal of medicine

Published: October 27, 2023

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.

Journal: JAMA

Published: October 25, 2023

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.

Journal: JAMA

Published: April 11, 2023

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.

Journal: JAMA

Published: December 16, 2022

Showing 1-12 of 22

Last Updated: 09/26/2026