Marta Calbet
R&D Center, Sant Feliu De Llobregat
Barcelona, CT, Spain
Barcelona, CT, Spain
Last Updated: 09/26/2026
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Found 16 publications
Discovery of LAS194046: A Potent and Selective pan-Janus Kinase (JAK) Inhibitor with a Suitable Profile for Inhaled Administration.
Journal: Journal of medicinal chemistry
Published: January 16, 2026
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
Journal: The Journal of clinical investigation
Published: January 31, 2023
The pan-JAK inhibitor LAS194046 reduces neutrophil activation from severe asthma and COPD patients in vitro.
Journal: Scientific reports
Published: September 15, 2021
Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases.
Journal: Journal of medicinal chemistry
Published: October 15, 2019
Novel Inhaled Pan-JAK Inhibitor, LAS194046, Reduces Allergen-Induced Airway Inflammation, Late Asthmatic Response, and pSTAT Activation in Brown Norway Rats.
Journal: The Journal of pharmacology and experimental therapeutics
Published: January 03, 2019
Discovery of a Novel Inhaled PI3Kδ Inhibitor for the Treatment of Respiratory Diseases.
Journal: Journal of medicinal chemistry
Published: October 24, 2018
PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge.
Journal: Biomarker research
Published: November 01, 2017
Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy.
Journal: Pharmacological research
Published: February 25, 2016
Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists.
Journal: European journal of medicinal chemistry
Published: December 03, 2015
Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists II: lead optimization.
Journal: Bioorganic & medicinal chemistry letters
Published: July 04, 2014
Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of pyrrolopiperidinone acetic acids as CRTh2 antagonists.
Journal: Bioorganic & medicinal chemistry letters
Published: July 04, 2014
Last Updated: 09/26/2026