Marta Giorgis
Via Pietro Giuria 9
Turin, 10125, Italy
Turin, 10125, Italy
Last Updated: 09/26/2026
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Found 32 publications
LogPpred: An AI-Based Predictive Model for Accurate Estimation of Molecular LogP.
Journal: Molecules (Basel, Switzerland)
Published: June 17, 2026
Targeting dihydroorotate dehydrogenase (hDHODH) beyond the barrier: discovery of MEDS700 as blood-brain barrier permeable hDHODH inhibitor.
Journal: European journal of medicinal chemistry
Published: January 27, 2026
Structure-based design of new pyrazole inhibitors targeting Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).
Journal: European journal of medicinal chemistry
Published: December 22, 2025
Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists.
Journal: Journal of medicinal chemistry
Published: October 22, 2025
Fluorescent Isostere (Fluostere) of the Carboxylate: Design of hDHODH Fluorescent Inhibitors as Proof of Concept.
Journal: Journal of medicinal chemistry
Published: June 18, 2025
Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.
Journal: ACS pharmacology & translational science
Published: September 04, 2024
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein.
Journal: Molecules (Basel, Switzerland)
Published: November 14, 2022
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety.
Journal: Journal of medicinal chemistry
Published: September 26, 2022
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study.
Journal: Molecules (Basel, Switzerland)
Published: May 10, 2022
Multitarget Antioxidant NO-Donor Organic Nitrates: A Novel Approach to Overcome Nitrates Tolerance, an Ex Vivo Study.
Journal: Antioxidants (Basel, Switzerland)
Published: November 05, 2021
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia.
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia.
Journal: Cell death & disease
Published: August 15, 2021
Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor.
Journal: Molecules (Basel, Switzerland)
Published: June 14, 2021
Last Updated: 09/26/2026