Martijn H. Brugman

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 31 publications

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.

Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.

Journal: Human gene therapy
Published: July 25, 2024

Pre-treatment with systemic agents for advanced NSCLC elicits changes in the phenotype of autologous T cell therapy products.

Pre-treatment with systemic agents for advanced NSCLC elicits changes in the phenotype of autologous T cell therapy products.

Journal: Molecular therapy oncolytics
Published: May 05, 2023

Identification of a small molecule for enhancing lentiviral transduction of T cells.

Identification of a small molecule for enhancing lentiviral transduction of T cells.

Journal: Molecular therapy. Methods & clinical development
Published: April 21, 2023

Multiple Genes Surrounding Bcl-xL, a Common Retroviral Insertion Site, Can Influence Hematopoiesis Individually or in Concert.

Multiple Genes Surrounding Bcl-xL, a Common Retroviral Insertion Site, Can Influence Hematopoiesis Individually or in Concert.

Journal: Human gene therapy
Published: October 05, 2020

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian.

Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian.

Journal: Leukemia
Published: June 18, 2020

Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct.

Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct.

Journal: Molecular therapy. Methods & clinical development
Published: April 28, 2020

Functional definition of a transcription factor hierarchy regulating T cell lineage commitment.

Functional definition of a transcription factor hierarchy regulating T cell lineage commitment.

Journal: Science advances
Published: January 19, 2019

CD4 T-cell cytokines synergize to induce proliferation of malignant and nonmalignant innate intraepithelial lymphocytes.

CD4 T-cell cytokines synergize to induce proliferation of malignant and nonmalignant innate intraepithelial lymphocytes.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 05, 2017

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: December 25, 2016

Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms.

Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms.

Journal: Experimental hematology
Published: May 26, 2016

The functional relationship between hematopoietic stem cells and developing T lymphocytes.

The functional relationship between hematopoietic stem cells and developing T lymphocytes.

Journal: Annals of the New York Academy of Sciences
Published: January 17, 2016

High Levels of Canonical Wnt Signaling Lead to Loss of Stemness and Increased Differentiation in Hematopoietic Stem Cells.

High Levels of Canonical Wnt Signaling Lead to Loss of Stemness and Increased Differentiation in Hematopoietic Stem Cells.

Journal: Stem cell reports
Published: October 22, 2015
Showing 1-12 of 31

Last Updated: 09/26/2026